| Chemiluminescence (CL) can be defined as the characteristic emission of radiation from a molecule, in an excited electronic state, produced in a chemical reaction. It can take place in the gas, liquid and solid phase. In recent years, CL has become a powerful analytical tool for selective and sensitive detection of chemical species. CL applications in analytical chemistry have numerous advantages such as high sensitivity, a wide linear range, simple and inexpensive instrumentation, and considerable reduction of the background noise. There are numerous reports supporting the importance of chemiluminescent methods in analytical chemistry, including a great variety of fields such as food, biomedical, anyway as detection system.Flow-injection chemiluminescence (FI-CL), which combines chemiluminescence (CL) and flow-injection, has high efficiency and accuracy. It becomes more and more important in pharmaceutic and pesticide residue analysis. The dissertation is composed of four chapters as followings:Chapter 1: Introduced the CL, FI and FI-CL, and their application in analytical field, paid more attention to the application in pharmaceutic and pesticide residue analysis. At last pointed out the purpose of the dissertation.Chapter 2: It was found that the weak chemiluminescence produced from the reaction of dextromethorphan hydrobromide with KMnO4 in acidic solution could be strongly enhanced by Na2SO3. Based on this found, a new flow injection chemiluminescence method is proposed for the determination of dextromethorphan hydrobromide. Under the optimized conditions, the proposed method allows the measurement of Dextromethorphan Hydrobromide over the range of 1.0 × 10-8 to 1.0 ×10-5 g/ml with a detection limit of 3.5 × 10-9 g/ml, and the relative standard deviation for 9.0 × 10-7 g/ml Dextromethorphan Hydrobromide (n = 11) is 2.20%. The... |
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