Synthesis And Characterization Of Acylating Derivatives Of 2, 2-Bisferrocenylpropane

In this paper, acylation of 2,2-bisferrocenylpropane is carried out by means of acid anhydride in the presence of boron trifluoride and methylene chloride. A series of acylating derivatives of 2,2-bisferrocenylpropane have been prepared by the Friedel-Crafts reaction. Some of the ketones were reduced to the corresponding a-hydroxyalkyl and alkyl derivatives of 2,2-bisferrocenylpropane with LiAlH4 and Zn(Hg)/HCl. The products of acylation and reduction were isolated by column chrornatography with neutral aluminum oxide. Furthermore, (6-carboxyl) -bisferrocenylpropane and (6,6'-bicarboxyl)-bisferrocenylpropane were synthesized from 6-(o-chloride-benzoyl)-bisferrocenylpropane and 6,6' -bi(o-chloride-benzoyl)- bisferrocenylpropane with t-C4H9OK in ethylene glycol dimethy ether as solvent. In addition, a series of carboxylic acid esters and acid amides were prepared from (6-carboxyl)-bisferrocenylpropane. All of them are new compounds, the compositions and structures of these compounds were characterized by elemental analysis, IR spectrum and 1FTNMR spectra. The synthesis condition and appropriate material ratio were also confirmed.