Synthesis, Crystal Structure, Bioactivity, Magnetic Properties Of Several Metal Complexes With Bioactive Ligand

Some metal complexes have occupied a central role in the development of coordination chemistry, this is manifested by the huge number of publications ranging from pharmaceutical chemistry to biochemical relevant studies. In this paper, we report the Synthesis, Crystal Structure, Bioactivity, Magnetic Properties of Several Metal Complexes with Bioactive Ligand.The first series of complexes is that three unprecedent compounds {[Cu(C4H5O4N)2(C7H6N2S)]?(CH3CN)} n(1), [Cu(C6H5CO2)2(C7H6N2S)]2(2)and Zn(C7H6O3)2 (C7H6N2S)2(3). The X-ray diffraction analysis revealed structure of the three complexes. Compound 1: it belongs to monoclinic with grace group P21/c,molecular formula: C13H14CuN4O4S,Mr= 385.88,cell parameters:a= 10.232(2) ?, b= 7.9590(14)?,c= 19.834(4) ?,β= 108.662(4) o,Z= 4,V= 1530.3(5) ?3,Dc= 1.675 Mg/m3,the Cu(II) is five-coordinated by one N atom from an 2-aminobenzothiazole(ABT) ligand, one N atom and two O atom of a terdentate chelating iminodiacetic acid(IDA) ligand, an O atom from another IDA of the adjacent unit [Cu(C4H5O4N)2(C7H6N2S)]?(CH3CN), this CuN2O3 coordination forms a distorted square-pyramidal. The two Carboxylic groups of IDA bond to the metal ion in the two coordinated modes: the monodentate and bridged bidentate. The complex is infinite one-dimesional linear chain formed by a repeating mononuclear structural unit bridged by IDA. Compound 2: it crystallizes in the monoclinic with space group P21/c,molecular formula: C42H32Cu2N4O8S2,Mr=911.92, cell parameters: a=10.310(2)?, b=18.121(4)?, c=10.566(2)?, β=106.619(4)o, Z=2, V=1891.6(7) ?3, Dc=1.601 Mg/m3, it is a centrosymmetric binuclear complex, each Cu(II) atom is five-coordinated in a square-pyramidal environment by one N atom from an monodentate ABT, four O atoms from four bridging bidentate benzoate. The distance of the two coppers connected by carboxylic bridges is 2.7011(9)?. Compound 3: it is in monoclinic with C2/c space group,molecular formula: C28H22N4O6S2Zn,Mr= 640.03,cell parameters: a=19.7628(12)?, b=22.5221(14)?, c=18.4465(11)?, β=90.939(3)o, Z=12, V=8209.4(9)?3, Dc=1.553 Mg/m3, the cell unit of 3 is of three-molecular and in centrosymmetric structure revolving Zn(2) atom. Each Zn(II) atom is four-coordinated in tetrahedral geometry and surrounded by two N atoms from two ABT molecular, two O atoms of two salicylic acetate anions.The second series of complexes is the ternary complexes of toxin heavy metal [Cd(II) and Pb(II)] with indole-3-acetic acid (HIA) and 1, 10-phenanthroine (phen). The two complexes have different coordination environment. The space group of Cd(C10H9O2N)2(C12H8N2)(4)is P21/c, the crystalloids belong to monoclinic, molecular formula: C32H24CdN4O4,Mr= 640.95, cell parameters: a= 12.4378(8)?, b= 12.3442(8)?, c=8.2971(11) ?, β=106.223(1)o, Z= 4, V=2697.4(3) ?3, Dc=1.578 Mg/m3, the center metal Cd(II) is coordinated in a distorted octahedral geometry and surrounded by two N atoms from one phen ligand and four O atoms from two IA anions. All ligands are in bidentate coordinated mode. Pb(C10H9O2N)2(C12H8N2)(5): it belongs to monoclinic crystal system, space group is is P21/n, molecular formula: C32H24N4O4Pb,Mr=735.74, cell parameters: a=12.8592(19) ?, b=13.0736(16)?, c=17.064(3)?, β=105.504(4)o, Z=4, V=2764.4(7) ?3, Dc=1.768 Mg/m3, the central metal Pb(II) atom is five-coordinated with three O atoms from two IA anions and two N atoms from one phen ligand, this PdN2O3 coordination forms an axially elongated square-pyramidal. The two carboxylic groups are bonded to metal ion in monodentate and bidentate mode respectively.The third series of complexes is transition metal Co(III) with tridentate Schiff base obtained from pyridin-2-carboxaldehyde and thiosemicarbazole. The singal crystal X-ray diffraction revealed that [Co(C7H7N4S)2] · ClO4 (6)belongs to triclinic crystal system with P-1 space group, molecular formula: C14H14ClCoN8O4S2, Mr= 516.83, cell parameters: a= 8.568(1)?, b=10.352(1)?, c=12.440(2)?, α=103.73(1), β=102.42(1)o, γ=100.16(1), Z=2, V=1016.3(3) ?3, Dc=...