| This project is a part of the theme that need draw the in Salvia miltiorrhiza Bunge aqueous solution composition in high stress which entrusted by the second factories of traditional Chinese medicine in Harbin. This project requires that protocatechuic aledhyde content can be forecasted fastly and accurately using near infrared spectrum technic combination with chemical metrology method.In recent years, with the trend of regressing nature more and more advocated in western country ,traditional Chinese medicine with its characters of natural and of little negative effect is accepted by every countries in the world and a market of traditional Chinese medicine of globalization is forming gradually. Now because government want to make the traditional Chinese medicine stabilizing production and long period development, relevant department points out that our country must possess own preponderant kinds and on this foundation we should establish the merchandise base of medicinal material with certain scale and market competition ability, and carry out industri- alization. In recent years our nation focus on industrialization production operation of sixty key preponderant kinds such as Salvia miltiorrhiza Bunge, ginseng and rehmannia glutinosa,and establish a batch of production base of medicinal material producting with good quality, high technological content, stabilizing channel of prod- uction and marketing and has certain relative scale and economic advantage.The agricultural slogan of traditional Chinese medicine is also begin pregnant with times developing. From above situation we can find out Salvia miltiorrhiza Bunge possess great share in dustry of troditional chinese medicines , it is important to develops the med- icine in our country .It is a typical exemple that composed Salvia miltiorrhiza Bunge dript pellet is the first preparation made in china which pass by America FDA.Pharmacology proves that Salvia miltiorrhiza Bunge have efficacy which meliorate crest form cycle, restrain thrombus disease and resist the inflammation. But for the pharmic research of chemical compos- ition of Salvia miltiorrhiza Bunge aqueous solution is just spread out in recent years. As a kind of important composition in Salvia miltiorrhiza Bunge injecting liquid, protocatechuic aledhyde can reduce blood viscosity apparently, resist to congeal, resist thrombus, promote fibre dissolve and reduce the blood plasma viscosity, improve tiny circulating, makes the blood velocity in tiny circulating occurs obstacle become quickly, clear away free base and protect heart brain anoxic and filling hurt again, protect liver, protect kidney, resist digestion ulcer, diminish inflammation.Therefore for mensuration of content of Protocatechuic aledhyde in Salvia miltiorrhiza Bunge is particularly important. And traditional chemical method is time-consuming, strenous, can not satisfy the requirement of fast analysis.And when measuring chemical composition, the reagent that added have destroied medicine original composition, make medicine being measured, can not be used repeatedly.It is near-infrared spectrum technology (near-infreied) that is called the green measure technology in 21 century; it is a technology that gets quick development in recent years. NIR has some following advantages:That absorption coefficient of a lot of material in near infrared area is little, make analysis course become simple. Near infrared light can penetrate through glass or quartz medium. Investment and operating spend low. It can be used to determine in nature of sample the, can also get the very high precision ration result. Do not destroy sample, do not use reagent, so do not pollute environment. Mensuration speed is very rapid.Near infrared spectrum that aera denote normally 1100-2500nm the spectrum district, near infrared spectrum locate besides the visible light ( 400 nm-700 nm ) can analyse the biology minute group .NIR can survey organic matter as well as partial inorganic substances as a kind of analysis me... |
PDF Full Text Request