Study On The Synthesis Of Methanone Cyclohexylphenyl

Methanone cyclohexylphenyl is an important organic medium material of medicine and dyestuff.In this thesis,the synthesis of methanone cyclohexylphenyl was studied.The problem of producing methanone cyclohexylphenyl to "Enviromentally Friendly Chemistry" was settled exploringly.Main studies as follows:1 The traditional route of methanone cyclohexylphenyl synthesis was improved.Phosphor trichloride substituded dimethylsulfoxide in the old route.The method avoided letting out toxic gas sulfur dioxide,simplified operation craftswork and saved energy. Operation craftwork was experimented and analyzed.In the suitable operating conditions,the yield of methanone cyclohexylphenyl was 81.3%.2 Several solid acidic catalysts were used and studied in the Friedel-Crafts acylation reaction of synthesis of methanone cyclohexylphenyl.Their catalysis activities were studied to select a better solid acidic catalyst fitting this system.This study divided into four parts as follows:(l).The three types of H- P ,H-Y and HZSM-5 zeolites were studied.The effection of calcination temperature,specific use of catalysts,reaction temperature and reaction time to the methanone cyclohexylphenyl yield were analyzed.The suitable operating conditions were got.(2).The application of the solid superacids-cation exchange resin A1C13 in methanone cyclohexylpheny synthesis was studied.The effection of specific use of catalyst, reaction temperature and reaction time to the methanone cyclohexylphenyl yield were analyzed.The suitable operating conditions were got.(3) The application of the SO2"4/MxOy solid superacid in methanone cyclohexylpheny synthesis was studied. Calcination temperature of SO2 4/Al2O3 and SO2yZr02,specific use of catalysts, reaction temperature and reaction time to effect methanone cyclohexylphenyl yield were analyzed.The suitable operating conditions were got.(4). The application of the tungstophosphoric heteropoly acid in methanone cyclohexylpheny synthesis was studied. Specific use of catalyst, reaction temperature and reaction time to effect methanone cyclohexylphenyl yiely were analyzed.The suitable operating conditions were got.3 Cyclohexyl acid was used in acylation reagent of Friedel-Crafts acylation reaction and theeroding problem of the old reactant cyclohexyl acyl chloride was solved.The catalysis activity of zeolites in this reaction was studied. The suitable operating conditions were got.In the condition,the yield of methanone cyclohexylphenyl was 12.8%.