The Effect On Electrical Characteristics Of Cell Membrane By Low-Frequency Electromagnetic Irradiation

With the development of the telecommunications and the morden industry electromagnetic fields has become more extensive effect on the human. Many magnetic healing instruments have come out, and some have already applied in clinic,but its mechanism has not been identified.So needs further study and explore.In this paper, form the experimental and theoretical view,we study the effect on the cell membrance electrical properties.The electrophysiological properties of ion channels under the low-frequency sine wave magnetic irradiation were studyed using the whole-cell patch clamp technique. Analysis the current characteristics of the whole cell and the potassium channel,IA changed in a time-dependent. Discussed the sine wave magnetic fields that frequency is 50Hz and the intensity is 0.5mT was imposed on the acutely isolated rat cortical neurons, the amplitudes of IAcurrent and the kinetic characteristics of steady-state activation and inactivation altered. The results show that sine wave magnetic fields can change the current amplitudes of the ion channel and the curves of activation and inactivation were changed by low-frequency magnetic irradiation. Changed properties of ion channels can effect the process of the action potential depolarization and hyperpolarization which might contribute to the restoration of damaged neuron.Paper based on Hodgkin—Huxley model,induced the parameters of the electrical field,which effect the membrane voltage variation with time. Simulation show that without electric field,the action potential can continuous release with the changed of some parameters;the action potential can mutation with the changed of electrical parameters.This may well explain the diseases caused by electro-magnetic exposure and the aberrance phenomenon on action potential...