| In this dissertation, high quality CdS nanocrystals (CdS QQ) with a narrow size distribution had been successfully synthesized through a reverse micelle route. In this route, hydrogen sulfide and CdCl2·2.5H2O were used as the sources of S2- and Cd2+ ions, respectively. An observation of transmission electron microscopy (TEM) on the shape of the CdS nanocrystals showed that the nanocrystals were about 5~7nm in size. Also, investigation into the optical properties of the nanocrystals was conducted with UV-Vis absorption spectroscopy and photoluminescence emission (PL) spectroscopy. There was blue shift of Qdots in UV-Vis and PL spectra compared to bulk material. The CdS QD possesses unique optical properties which were promising in bio-labeling relevant applications as a biological probe.Then surfaces of CdS Qdots were modified with mercaptoacetic acid (MAA), so that the QD can be dispersed in the water environment since the QD wants to be used as bio probing in the cell biology research. Furthermore, folic acid was attached to the surface of CdS QD via the MAA. In the end the Folate Receptor (FR)-targeting QD was fabricated.In this experiment, the HepG2 cells which express high level for Folate Receptor were employed to conduct the cell-targeting trial. The results indicated that the FR-targeting QD can positively adhire to the HepG2 cells, which confirmed that the FR-targeting QD can be used as effective bio-probing in the cell biology research.To realize the control over the release of the QD, the Photocontrolled of conjugated CdS QD was proposed in this experiment and it had been attained initially. Through the phenylazophenylalanine (PAP) surface modification for the CdS QD, the QD can be controlled by ultraviolet. This may be the first step to fabricate the robust reversible QD with manipulated controllability which will be received wide attention and application in biology rerearch.
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