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One Optimal Adaptive Design In Clinal Trials

Posted on:2007-10-24Degree:MasterType:Thesis
Country:ChinaCandidate:L CaoFull Text:PDF
GTID:2120360182499076Subject:Probability theory and mathematical statistics
Abstract/Summary:PDF Full Text Request
We consider the clincal trials scenario where patients enter the trial sequentially and the experimenter taking humanism into consideration has to adaptively select the better of the two competing treatments for future application. We make the power function maximize under certain statistical standard. Power function is the function of parameters a and /3 which belong to Generlized Friedman's Urn model.
Keywords/Search Tags:Generlized Friedman's Urn model, Adaptive designs, power function, strong convergence, asymptotical normality
PDF Full Text Request
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