A Study On Abdominal Pain Of Traditional Chinese Medicine And Its Syndrome Differentiation And Treatment

At present,for some common clinical diseases with abdominal pain as the main manifestation,serious physical and mental impact occurs on patients for the lack of effective drugs.After thousands of years,Chinese medicine forms its perfect and unique medical system.Nowadays,Chinese medicine has a good clinical effect on abdominal pain diseases whose recurrence occurs frequently,but a gap still lies in the way of satisfying results.Therefore,it is urgent to excavate the ancients’ cognition,enrich the methods,and learn the law of medication from the classics of traditional Chinese medicine.Objective:By collecting and referencing a large number of ancient and modern documents,the definition and scope of abdominal pain is settled down;secondly,according to the name,etiology,pathogenesis and treatment,literature of abdominal pain in TCM classics are investigated;then,four ways of abdominal pain differentiation and treatment are discussed;finally,data excavation of formula patterns in ancient prescription is deployed.Methods:On one hand,contemporary documents collection is applied,under the guidance of"material resource textology" and the records related to abdominal pain is investigated from the aspects of name,pathology,etiology and treatment as well as its definition,sphere,syndrome differentiation and six meridians differentiation;Secondly,in statistical research methods,with information technology,data excavation of 429 ancient prescriptions for abdominal pain treatment is deployed.Drug frequency,four qi,five flavors,meridian pertaining are analyzed.Apriori algorithm SPSS Modeler 18.0 was used to analyze association rules and association network diagram was thus printed.Finally SPSS Statistics 24.0 was used for cluster analysis.Results:The research content of this paper is mainly divided into four parts.The first part:through systematically sorting and analyzing information from ancients classics and combing with the latest clinical research,it is considered that the definition and scope of abdominal pain in Chinese Medicine is debatable.It is proposed to revise it as"abdominal pain refers to the syndrome of abdominal pain as the main disease caused by the stagnation qi of the viscera and meridians,or the loss of warm nourishment under the influence of internal and external factors".For its scope,the ancients often put stomach pain,hypochondriac pain,heartache,chest pain etc.into its category which should be removed from the category of abdominal pain.Modern diseases such as acute and chronic pancreatitis,mesenteric and peritoneal lesions,incomplete intestinal obstruction,postoperative intestinal adhesion,irritable bowel syndrome,ulcerative colitis,intestinal parasites,abdominal Henoch-Schonlein purpura,extrahepatic cholelithiasis and inflammation can be treated with reference to TCM abdominal pain syndrome.The second part:through collecting and sorting out the ancient Chinese medicine literature,the name,etiology,pathogenesis and treatment of abdominal pain in ancient books are systematically analyzed.①As far as the name of abdominal pain is concerned,the term abdominal pain was first recorded in Shanhai Jing,and as an independent disease syndrome,it was first recorded in the Theory of various Diseases.②As far as the etiology of abdominal pain is concerned,there are many external causes,such as the evil of six lewd senses,the change of five movements and six qi,and some foul substances in nature,which can attack the human body and cause abdominal pain.③According to the pathogenesis of abdominal pain,the common pathogenesis can be summarized as four kinds:cold coagulation,qi and blood imbalance,deficiency of qi and blood,and disorder of viscera.④In terms of the treatment of abdominal pain,this study focuses on the internal treatment of traditional Chinese medicine,and it is believed that sweat,vomiting,purging,warm,clear,eliminate,and nourish methods can be used in the clinical treatment of abdominal pain.The third part:combining ancient and modern literature,from the differentiation and treatment with angels of pattern,location,six meridians and combined with disease.①On pattern differentiation and treatment of abdominal pain,based on the etiology and pathogenesis,the syndrome of abdominal pain are classified into wind-cold external guest syndrome,dry fire external guest syndrome,summer heat dampness external guest syndrome,cold evil internal obstruction syndrome,heat heat internal accumulation syndrome,phlegm dampness stagnation syndrome,diet stagnation syndrome,qi stagnation stagnation syndrome,liver and spleen disharmony syndrome,blood stasis internal disturbance syndrome,middle asthenia cold syndrome,a total of 12 syndromes,and the corresponding syndromes are identified,with treating methods are listed respectively.②On the location of abdominal pain treatment,through the collation and analysis of ancient books,the ancients have put forward the idea of division of abdominal pain treatment.The ancients had five methods to divide and treat the whole abdomen by division,three yin by division,three coke by division,umbilical as the center,and the whole abdomen by comprehensive division.Based on this,it is proposed to divide abdominal pain into epigastric pain,umbilical abdominal pain,small abdominal pain,less abdominal pain,hypochondriac abdominal pain and lumbar abdominal pain according to the pain site.③As for six meridians of the diagnosis and treatment of abdominal pain:Taiyang abdominal pain,Yangming abdominal pain,Shaoyang abdominal pain,Taiyin abdominal pain,Shaoyin abdominal pain,Jueyin abdominal pain.④As for the syndrome differentiation and treatment of abdominal pain,it is considered that the new model of clinical integration of "disease" and"syndrome" of traditional Chinese medicine has been widely used.Therefore,acute pancreatitis,chronic pancreatitis,ulcerative colitis,Crohn’s disease,irritable bowel syndrome,intestinal adhesion,abdominal Henoch-Schonlein purpura and other diseases generally recognized by modern Chinese medicine scholars can be attributed to TCM abdominal pain syndrome as the research object,the research progress of the combination of its disease syndrome is summarized,and some views are put forward on this basis.The fourth part:With the help of information technology,data excavation on 429 ancient prescriptions for abdominal pain are applied.By frequency analysis,of the 55 high-frequency incited drugs,herb with warm nature(612 times,24.11%),tonifying nature(612 times,24.11%),and regulating qi nature(528 times,20.80%)are dominating.The top three four-flavors are warm(1364 times,42.56%),flat(540 times,16.85%),heat(326 times,10.17%).Five flavors listed top are Pungent(1508 times,47.05%),bitter(848 times,26.46%),sweet(729 times,22.75%),meridian pertaining is spleen,stomach and liver.Through associating rules,18 combinations were found.By systematic clustering analysis combining with traditional Chinese medicine,finally,10 clustering parties are obtained.Tips:the ancients have the following basic ideas and characteristics in the treatment of abdominal pain:Pungent warm and pungent heat medicines are adopted to warm the gastric cavity and regulate menstruation;bitter warm and pungent warm medicines adopted to regulate qi,invigorate blood and dry dampness;Sweet warm and sweet flat medicines are adopted to relieve pain and tonify deficiency;bitter cold medicines are applied to clear fire and purge cold accumulation.