Synthesis,Properties And Applications Of Inorganic Te-O Backbone Polymer:Polytelluoxane

Construction of polymer main chain is an inevitable procedure for the advancing of polymer science.The appearance of new polymers is expected to provide powerful toolkits for the upgrading of industry and the revolution of technology.In this paper,the creation of polytelluoxane(PTe O),an unprecedented polymer with an inorganic main chain constituted of tellurium and oxygen is reported.The related synthetic method and molding process of PTe O have been developed with potential industrial prospects.The characteristic physical and chemical properties of PTe O are studied.The possible applications of PTe O in optical materials,degradable materials,biomedicine and other fields are explored.The main achievements of this paper are demonstrated as follow:1.Synthesis,property investigations and potential applications of PTe O: We have constructed a new polymer with tellurium-oxygen main chain structure and carried out detailed structural characterization;Through interfacial oxidation polymerization,we have realized the batch preparation of polytelloxane under mild conditions,and designed the molding and processing scheme of bulk materials and film materials for PTe O;Through the study of its optical properties,we found that the ultraviolet protection performance and visible-near infrared high transmittance performance of PTe O materials;Through the study of its response to light stimulation,we found that the light activation of the main chain structure of PTe O and its potential application in the photo-deposition of platinum and the photocatalytic oxidation of alcohols to ketones;By studying the redox stimuli-responsievness of PTe O,we found that PTe O to be a closed-loop recyclable material with a mild degradation reaction condition and good repeatability and related operation protocols with good atomic economy and environmental friendliness are designed.2.Intracellular oxidative polymerization of PTe O: Making use of the coordination ability and the redox stimuli-responsievness of tellurium,we prepared tellurium-gold nanoparticles in order to overcome the existing challenges in the field of polymerization in living cells such as difficult monomer transmembrane transport,interference of bioactive substances,and low energy transfer efficiency.The condition of “low overall concentration and high local concentration” was designed for the intracellular polymerization.Under the mediation of tellurium-gold nanoparticles,we could take reactive oxygen species(ROS)in biological environment as resources to conduct oxidative polymerization in situ and synthesize PTe O in living cells.Moreover,the synthesis of PTe O could be selectively carried out inside cancer cells by taking advantage of the difference in the concentration of ROS between cancer cells and healthy cells.At the same time,through the interaction between PTe O and the antioxidant system inside cancer cells,a self-amplification process could be realized and the apoptosis of cancer cells could be induced selectively.In addition,we verified the potential clinical effectiveness and biological safety of intracellular oxidative polymerization through animal experiments.