| Objectives:Coronary artery bifurcation lesions,which is a major dilemma faced by percutaneous coronary intervention(PCI),account for about 15-20%of all coronary lesions.Nowadays,the success rate of the operation on bifurcation is still not optimistic.It is controversial that which strategy is better.The purpose of this study is to explore independent risk factors for single-stent failure,so that operators are able to adjust treatment strategies more efficient.Methods:1601 patients met the criteria and were divided into single-stent failure group(N=106)and the single-stent non-failure group(N=1495).We collected the clinical baseline data of patients,the characteristics of coronary angiography,characteristics of interventional treatment and data of Quantitative Coronary Angiography analysis(QCA).Variables with p<0.25 in single factor analysis were filtrated and put into multivariate logistic regression analysis to recognize independent factors for single-stent failure.Results:Multivariate regression analysis showed that independent risk factors for stent failure included::true bifurcation lesions(odds ratio:2.493,95%confidence interval 1.509-4.120,p<0.0004),TIMI rate of side branch<3 before stent placement in main branch(odds ratio:19.900,95%confidence interval 8.073-49.052,p<0.0001),jailed wire technique(odds ratio:0.540,95%confidence interval 0.296-0.988,p<0.0456),stenosis degree of bifurcation core before operation(%)(odds ratio:1.011,95%confidence interval 1.002-1.019,p<0.0143),bifurcation angle(odds ratio:1.019,95%confidence interval 1.009-1.030,p<0.0004),reference diameter between main branch and side branch(ratio:5.508,95%confidence interval 2.774-10.936,p<0.001),stenosis degree of side branch after the pre-expansion(ratio:1.020,95%confidence interval 1.009-1.031,p<0.0021).Conclusion:7 variables are identified as independent risk factors for single-stent failure.More prospective studies are needed to prove the results. |
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