Biochemistry and cell biology of the human interferon-gamma receptor: Biosynthetic analysis and demonstration of ligand-induced receptor phosphorylation
Posted on:1993-10-25
Degree:Ph.D
Type:Dissertation
University:Washington University in St. Louis
Candidate:Khurana Hershey, Gurjit Kaur
Full Text:PDF
GTID:1474390014996484
Subject:Immunology
Abstract/Summary:
Interferon-gamma is a potent immunomodulatory cytokine that exerts its pleiotropic effects through a high affinity interaction with a specific receptor expressed at the target cell surface. Although the primary structures of the human and murine IFN...