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The effect of long chain saturated fatty acids (12:0, 14:0, 16:0, 18:0) on hepatic cholesterol metabolism

Posted on:1998-07-27Degree:Ph.DType:Dissertation
University:University of MinnesotaCandidate:Kim, Jeong-Sook LeeFull Text:PDF
GTID:1464390014975543Subject:Health Sciences
Abstract/Summary:
Plasma and hepatic cholesterol responses to dietary cholesterol (0, 0.006, 0.06%) and fatty acid chain length (12:0, 14:0, 16:0, 18:0) were investigated in the Mongolian gerbil. Hepatic esterified cholesterol concentrations of animals fed 16:0 and 18:0 were elevated relative to those of animals fed 12:0 and 14:0 (P ;We examined the effect of in vitro long chain fatty acid supplementation on HepG2 cellular esterified cholesterol concentration. HepG2 cells were incubated for 24 hours with 0.5mM 12:0, 14:0, 16:0, 18:0, and 18:1 (FA:BSA molar ratios 1.2...
Keywords/Search Tags:Cholesterol, Chain, Fatty, Hepatic
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