Tropoelastin, the soluble precursor protein of insoluble elastin, contains repeating units that function in providing both elasticity as well as cross-linking sites. Tropoelastin also contains a unique carboxy terminal domain encoded by exon 36 that may play a role in the process of insolubilization. Using expression vectors that encoded full length tropoelastin or tropoelastin devoid of the region encoded by exon 36, (... |