With the goal of obtaining enantioselective transaminase mimics, several synthetic schemes have been devised for doubly linking a pyridoxamine moiety through thioether linkages from the 2;The substrate selectivities of ;A number of cyclodextrin derivatives doubly functionalized with a pyridoxamine and a base have been synthesized and the stereoisomers separated. These transaminase mimics have been tested for optical induction in transamination reactions of... |