Development of small molecule activators of protein phosphatase 2A (SMAPs) for the treatment of prostate cancer

Posted on:2017-03-27

Degree:Ph.D

Type:Dissertation

University:Icahn School of Medicine at Mount Sinai

Candidate:McClinch, Kimberly

Full Text:PDF

GTID:1454390008964037

Subject:Cellular biology

Abstract/Summary:

This study examined the role of a novel series of small molecule activators of protein phosphatase 2A (PP2A) on preclinical models of castration resistant prostate cancer (CRPC). (Abstract shortened by ProQuest.).

Keywords/Search Tags:

Phosphatase 2A, Protein phosphatase, Small molecule activators, Prostate cancer

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