Font Size: a A A

Application of singular value decomposition to DNA microarray

Posted on:2006-07-14Degree:Ph.DType:Dissertation
University:University of Illinois at ChicagoCandidate:Niknejad, AmirFull Text:PDF
GTID:1454390005995655Subject:Mathematics
Abstract/Summary:
In the last decade, molecular biologists have been using DNA micro-arrays as a tool for analyzing information in gene expression data. During the laboratory process, some spots on the array may be missing due to various factors, for example machine error.; We suggest here a new method of the estimation of missing entries in a gene expression matrix, which is done simultaneously-i.e., the estimation of one missing entry influences the estimation of other entries. Our method is closely related to the methods and techniques used for solving inverse eigenvalue problems.
Keywords/Search Tags:Gene expression
Related items