| My research addressed optimization models for radiation therapy treatment planning and patient scheduling. In intensity modulated radiation therapy (IMRT) treatment planning problems, I use direct aperture optimization (DAO) that explicitly formulates the fluence map optimization (FMO) problem as a convex optimization problem in terms of all multileaf collimator (MLC) deliverable apertures and their associated intensities and solve it using column generation method. In addition, the interfraction motion has been incorporated to the stochastic-programming based FMO and DAO models. Optimization models for patient scheduling problems in proton therapy delivery have also been studied in this research. (Full text of this dissertation may be available via the University of Florida Libraries web site. Please check http://www.uflib.ufl.edu/etd.html)... |
