Acute and chronic contractile activity-induced adaptations in muscle and mitochondrial function

xercise training is a potent stimulus for favourable phenotypic adaptations in muscle, including the induction of mitochondrial biogenesis. Although the occurrence of organelle expansion in response to chronic muscle use is accepted, the cellular events governing this remodeling are undefined. Thus, the purpose of this Dissertation was to examine the acute and chronic contractile activity-induced adaptations in skeletal muscle and mitochondrial function in young and old animals.;In Manuscript ;The aim of Manuscript ;Manuscript ;The intracellular signals associated with contractile activity are important for the induction of downstream phenotypic plasticity. In Manuscript...