The Epidemiological Study On Sleep Quality And Body Composition In Women

Normal aging and western lifestyles involve critical changes to body composition,including skeletal muscle loss,increased fat mass and decreased bone mass.Hence,with aging and westernization of lifestyle,the prevalence of obesity,sarcopenia and osteoporosis rise sharply and become major public health problems.Women have higher probability in experiencing obesity,sarcopenia and osteoporosis than men because of especial physiological changes.Sleep is essential for daily life.Previous literatures suggest that sleep,which is closely associated with several endocrine and metabolic dysfunction have important impact on body composition.Women have a 50%-60%greater chance in suffering sleep problems and are more likely to be affected by poor sleep quality than men.The present study was designed to examine the relartionship between sleep quality and body composition,and tried to give some suggestions about body composition related chronic disease prevention strategies.Therefore,the present study focuses on women and contains thesis as follow:(?)Association between sleep quality and bone mineral density(BMD)in Chinese women across different age and menopausal status.(?)Associations of sleep quality with obesity,sarcopenia and sarcopenic obesity in different age groups.(?)The longitudinal relation between sleep quality and body composition in Chinese women.The main findings are summarized as follows:(?)Poor sleep quality was correlated to low total BMD and legs BMD in middle-aged(45-64 years old)women after adjusting for potential confounders.When further reran the regression models based on menopausal status(premenopausal,early postmenopausal and late postmenopausal)in middle-aged women,significant associations between BMD and sleep quality were observed only in premenopausal and early postmenopausal groups.(?)Poor sleep quality was significantly associated with higher BF%,lower RASM parameters after adjusting for potential confounders in Chinese women.Similarly,poor sleep quality was associated with high sarcopenia(OR=1.53,95%CI=1.03-2.30)and sarcopenic obesity(OR=1.96,95%CI=1.26-3.05)risk.In the age stratified analysis,we found that these associations were most robust in middle-aged women,especially 55-64 years old group.(?)In the longitudinal study,we found that compare to women with good sleep quality,women with poor sleep quality in the baseline have lower total and regional BMD and lose bone mass more sharply,indicating that poor sleep quality is a potential risk factor for osteoporosis.When further divided women into young group(<45 years old,premenopausal or early postmenopausal middle-aged women)and old group(late postmenopausal middle-aged women or ?65 years old),we only found the association between sleep quality and BMD in young group.However,we did not find similar results between sleep quality and sarcopenic obesity related parameters.In conclusion,we explored the relation between sleep quality and body composition in women in the present study and found that poor sleep quality was correlated to high osteoporosis,obesity,sarcopenia and sarcopenic obesity risk,especially in middle-aged group.In terms of body composition related disease prevention,it seems important for women to enhance sleep quality,especially in early time.These results of our study may lead to the development of better preventive approach to body composition related disease in women.