The Study Of Security And Availability In Endoscopic Versus Laparoscopic Resection For Gastric Gastrointestinal Stromal Tumors

Objective:Despite endoscopic resection has been performed to treat gastric gastrointestinal stromal tumor(GISTs).However,the safety and long-term outcomes remains controversial.This study aims to compare the safety and surgical outcomes of endoscopic versus laparoscopic resection of gastric GISTs.Methods:A total of 335 patients that were pathologically confirmed with gastric GISTs(tumor size ? 3.5 cm)were surgically treated with endoscopic resection(endoscopic group)or laparoscopic resection(laparoscopic group)in three institutions from March 1,2011 to October 1 2014.These demographics,tumor characteristics,and outcomes were retrospectively analyzed for identification of outcomes and feasibility of endoscopic or laparoscopic resection.Results:Of 335 patients,262 and 73 patients underwent endoscopic and laparoscopic resection,respectively.The average tumor size was 1.33±0.78 cm in the endoscopic group and 1.97±0.93 cm in the laparoscopic group.The average operating time was 62.40±36.94 min in the endoscopic group and 112.81±55.69 cm in the laparoscopic group.Days of realimentation was 2.76±1.67 in the endoscopic group and 4.89±2.03 in the laparoscopic group.The average cost was $ 3246.01±1017.61 in the endoscopic group and $ 4884.81± 1339.51 in the laparoscopic group.There was no postoperative mortality.Endoscopic resection for gastric GISTs is safe and feasible in tumors ?3.5 cm.Conclusion:Because endoscopic resection showed good results with lower operating time,realimentation days,length of hospital stay and mean total cost,it is a minimally invasive and safe alternative approach which can achieve fast recovery and satisfactory outcomes for appropriately selected patients with gastric GISTs.