| ObjectivePremature Ovarian Failure(POF)is caused by a variety of reasons of gynecological endocrine disease.Due to ovarian follicle depletion or iatrogenic injury,patients will have ovarian failure before 40 years old.Besides the reduction of the patient’s menstrual,too little of the amount,amenorrhea,infertility and a series of major clinical symptoms,patients often accompanied by varying degrees of perimenopausal syndrome symptoms,all these syndromes are seriously affecting the quality of life of patients and is kind of gynecological difficult disease.Reported in the literature,the incidence of POF in women accounted for 1%-3%,the incidence rate of the disease is on the upward trend in the past 20 years,the age of onset is also tend to be younger.This is the hot and difficult points on today’ s Reproductive Medicine and Reproductive Health Research.There is no record of "Premature Ovarian Failure" from the ancient books.According to its characteristics,it can be attributed to the Traditional Chinese Medicine as "Amenorrhea","Not in time","Not old but without menstruation","Dry blood","Infertility","Irregular menstruation stopped" or "Menstruation and never" and other areas of disease.Chinese Medicine Practitioners believe that the pathogenesis of the disease that kidney deficiency as its fundamental,there are some other doctors believe that spleen and kidney qi deficiency or kidney deficiency,liver depression,and heart,liver,spleen are closely related,mixed with deficiency and excess but mostly are deficiency mixed with addiction and sputum.The treatment from the Traditional Chinese Medicine is guided by the main concept of the "holism concept" of Chinese Medicine,dialectical treatment,that the kidney is the innate,the main reproductive,medication to kidney based on the same time dispersing stagnated liver qi and tonifying spleen,nourishing the heart to calm the mind refreshing and traquilzing and other treatment,enriching Chong and Ren meridian,so that Xuihai is full,profit and loss at times.Mainly through the syndrome differentiation treatment,unilateral prescription or experienced prescription treatment,sequential yin and yang sequential therapy,acupuncture treatment and integrated traditional Chinese and Western medicine treatment and other methods,give full play to multiple target point and multi-level of traditional Chinese medicine therapy.In recent years,many scholars,doctors made a series of in-depth exploration and made some progress in research on the disease from the pathogenesis,interpretation of the cause and the mechanisms of POF.Western medicine consider POF as a highly heterogeneous clinical,complicated and mixed cause of diseases,the etiology of complex pathogenesis is not clear,more than half of patients can not find the exact cause of POF clinically.From the data of research shows that genetic factors,gene mutations,enzyme factors,chromosome karyotype abnormalities,immune factors,metabolic abnormalities,drug effects,surgery and radiotherapy and chemotherapy damage,viral infection,environmental and psychological factors are likely to induce POF.POF treatment is more difficult,there is no clear and effective treatment measures on Western medicine,there is also no effective restoration or protection of the function of ovarian,mainly focus on age of the patients,etiology,symptoms,fertility requirements and other considerations.Clinical treatment programs,such as hormone replacement therapy(HRT),ovulation,assisted reproductive technology,immunotherapy,etc.However,the side effect is relatively high,and difficult to maintain the effect.The western doctor has not yet found a definite and effective method for the treatment of POF at present.Lingnan medicine has a long history,is an important part of traditional Chinese medicine,Lingnan culture and the crystallization of the blend of Chinese medicine culture.Lingnan medicine focuses on the general theory of traditional Chinese medicine under the guidance of the framework,combined with the unique regional culture,climate characteristics,medicinal resources,folk experience and unique diseases,common syndromes and other forms of unique theoretical system and clinical experience of regional medicine.Lingnan Chinese medicine gynecological school is an important subject classification of Lingnan medicine,Lingnan Chinese medicine gynecologist in the traditional Chinese medicine framework,the development of the Lingnan region from the academic characteristics of the medical system,to learn,medical and Inheritance relations constitute its main connotation.Lingnan Chinese medicine gynecological schools include the Guangzhou Luo’ s gynecology and Eastern Guangdong Chua’s gynecology two gynecological,and also include some other Lingnan gynecological and miscellaneous disease Chinese medicine practitioners.Lingnan Chinese medicine gynecological schools for the diagnosis and treatment of ovarian premature rupture of the disease and literature,records the medical life of many valuable theoretical understanding and clinical experience,the development of clinical gynecology of Chinese medicine has an important inspiration and reference.Lingnan gynecology began from the Qing Dynasty to modern era,Lingnan Chinese medicine gynecologist on the theory of ovarian premature rupture of the theoretical and clinical experience of scattered in this period of the book,the systematic collection,mining,analysis of these valuable information and information.For improving the awareness of the disease and the level of diagnosis and treatment have significant value and significance.Through the literature review and research progress,I found the Lingnan traditional Chinese medicine gynecological treatment of ovarian premature rupture of the academic frontier gaps:1.There is no expert,scholars systemtic in finishing,induction and analysing the syndrome Diagnosis and treatment of Lingnan Chinese medicine gynecologist for POF.From the current literature,is only limited to a doctor’s academic point of view and clinical experience,or the understanding of the disease,research and treatment scattered in other medical care,and most scholars only focus on the study of the medical records of some doctors,the use of medicine classification analysis,has not yet seen the ancient Lingnan Chinese medicine gynecologist for the treatment of ovarian premature rupture of the relevant system for the systematic literature;2.Retrieval of the recent 40 years Literature,there is still no specific literature study about the theory of sublimation point of view,a systematic study of Lingnan ancient Chinese medicine gynecologists diagnosis and the treatment of POF associated with the academic thinking,academic essence and clinical experience of the literature,no special academic Paper.It is not only helpful to explore the traditional Chinese medicine for the treatment of POF but to improve the curative effect,and to provide a theoretical basis and clinical reference for the treatment of POF.The clinical application of clinical practice,play a positive role in the future,but also conducive to give full play to the academic characteristics of Lingnan Chinese medicine gynecological medicine,is conducive to the Lingnan Chinese medicine academic thought inheritance and innovation method.MethodsLiterature research method together with Theoretical Analysis method is the starting point on this research.Literature Research includes data collection,identification,collation,compilation and so on.The Theoretical Analysis is the method of using classification analysis and clinical interpretation the experience of the ancient Lingnan Chinese medicine gynecologist diagnosis and treatment of POF syndrome.The academic experience,connotation and clinical value of Lingnan Chinese medicine gynecologist were analyzed.Access to the CNKI(1974-2017),a total of 3315 articles on POF were found,and there was no specific discussion on the diagnosis and treatment of POF in the history of Chinese medicine from the perspective of literature collating and theoretical sublimation.I found that there is a blank spot that so far no one had study or summerized the diagnosis and treatment of POF from the Lingnan Chinese medicine gynecologist.The research methods include two parts:Data collection and sorting and Analysis of Academic Theory.1.Data collection and sortingCollection of ancient books and compliation of research material on Lingnan Chinese medicine gynecologist.According to Lingnan Chinese medicine gynecologist in the era of division,divided into 4 periods:Prior to Qing Dynasty,the Qing Dynasty,the Republic of China period and the modern age.Select some representatives of the doctors and their writings,collect and collate relevant articles,literature.Before the election of the main selection of the Jin Dynasty Ge Hong’s "Bao Puzi nei wai pian","Zhou hou bei ji fang";Bao Gu related literature records;Zhi fa cun’ s "Zhi tai yi fang","Shen su fang";Luofu Shan Ren’s "Luzhu tan ji yan fang" and so on.Qing Dynasty,the main choice of Xie Wan Qing’ s "Hui jing chan yi",He Mengyao’ s "Fuke liang fang",Liu Yuan’s "Yi xiu zuan yao",He Shouyu’s"Guang si jin dan".During the period of the Republic of China,Lu Chubai’s"Fuke zuan yao jiangyi" was selected,and Xie Zelin’s "Fukezui jiang yi"was chosen.Modern doctors,the main selection of Guangdong Province,the old Chinese medicine is good at diagnosis and treatment of gynecological diseases experts.Among them,"The elderly Chinese Medicine of Guangdong Province"refers to 72 old Chinese medicine who attended the Guangdong Provincial Health Department organized the "Succession of elderly Chinese medicine academic experience forum" in 1962;and who attended the Guangdong Provincial People’s Government named "Guangdong Province elderly Chinese medicine" in 1978.Comprehensive selection of two experts list,screening out good at the treatment of gynecological diseases experts,widely collected in their publications published in various publications related to POF of the academic point of view,diagnosis and treatment experience,which has a systematic discussion and insightful elderly Chinese medicine:Wu Zhuo Shen,Shen Ding Sun,Ouyang Huiqing,Luo Zhenhua,Li Liyun.In addition,the selection of Lingnan two gynecological genre(Guangzhou Luo’ s gynecological genre and Eastern Guangdong Cai’s gynecological genre)of the successor:Luo Dihua,Luo Yuankai,Zhang Yuzhen,Luo Songping,Zhu Ling,Shi Yun,Zhao Ying,Liao Huihui,Zeng Lei,Cai Yang Gao and Cai Chunchen,To organize their published in various publications on the diagnosis and treatment of POF of the academic experience,the diagnosis and treatment of ovarian premature failure data and academic experience collected.2.Academic theory analysis.As the ancient Chinese medicine in the absence the record in the name of POF,only based on its characteristics to attribute to the ancient Chinese medicine in the "Amenorrhea","Not in time","Not old but without menstruation","Dry blood","Infertility","Irregular menstruation stopped" or "Menstruation and never" and other areas of the disease,so the collection of Lingnan Chinese medicine gynecologists diagnosis and treatment of POF associated with the disease data is very difficult,and therefore very valuable.Based on the time line,according prior to the Qing Dynasty,the Qing Dynasty,the Republic of China period and the modern period four time plate,select the history of Lingnan gynecologist on the data related to POF data analysis and review,including the characteristics of the medicine,the case of illness and other examples of analysis and theoretical concise,and strive to trace its origin,analyze the changes in the situation,sorting the period of Lingnan Chinese medicine gynecologist diagnosis and treatment of POF related theory,prescription compatibility rules and other valuable information,a comprehensive analysis and research for the diagnosis and treatment of premature ovarian failure in Lingnan provide a reference basis.In summary,the author of sort out from the Lingnan ancient Chinese medicine gynecologists diagnosis and treatment of POF associated with the literature as the object of study,the use of data mining methods,under the guidance of basic theory of Chinese medicine,to carry out Lingnan Chinese medicine gynecologists on POF etiology and pathogenesis,diagnosis and treatment.This paper focuses on the dialectical prescription medicine use characteristics and academic experience of the modern Lingnan Luo’ s gynecological genre and Cia’s gynecological genre,and uses the literature research method and the theoretical analysis method to carry on the research and collation of the literature and carry on the analysis and summarisation,concise academic point of view,and ultimately form the dissertations.Results1.Prior to Qing Dynasty,the selection of Ge Hong,Baogu,Zhi fa cun and Luofu Shan Ren four representative doctors,from the limited amount of data and records of information,we study the diagnosis and treatment of POF.Due to the development of productive forces the level of the restrictions on the understanding and diagnosis of the disease is not enough science,the exact effect.Start from the Jin Dynasty Ge Hong to the Ming Dynasty Luofu Shan Ren,the level of diagnosis and treatment continue to improve,from the initial basic stay in the level of folk medicine to gradually develop into more scientific understanding,diagnosis and treatment system under the guidance of the basic theory of Chinese medicine.Every physician is without exception,by their own social conditions,economic level,political environment,the impact of regional characteristics,in the long-term practice,the formation of their own unique and innovative understanding and experience:Ge Hong,he focus on the actual effect on his consultation,to alleviate the pain of patients,such as the use of Di yu and Gancao boiled water to relieve the vulva dry and other symptoms due from POF,it provides a good reference to the future generations of physicians.Compare to modern medicine,the use of estrogen topical relief symptoms,Chinese medicine outside wash to reduce side effects.Ge Hong not only pay attention to inheritance classic,but also dare to break the old legislation,which is to carry forward the Chinese medicine,growth,progress required indispensable spirit.For example,he inherited the theory of "Huangdi Nei Jing",attention to the role of physical fitness in the incidence;innovative use of animal and vegetable drugs used in the treatment of amenorrhea;Although not in the medical development of the Jin Dynasty,but he has begun to pay attention to the treatment.In the identification of disease classification,showing the treatment of gynecological disease syndrome differentiation,and formed a focus on prevention of "Zhi wei bing"thinking.Baogu as the first female moxibustion,to create a moxibustion adjuvant treatment of POF and other gynecological diseases laid the foundation to make an important contribution.Zhi fa cun used the existence of diagnosis and treatment of POF,the most important contribution is to create a "Yao zi yi wu fang",it reflects his academic thinking in focusing on supplement blood.Ming Dynasty Luofu Shan Ren with "Luzhu tan ji yan fang",can be described as a comprehensive medical books,from the contents of the book also reflects the theoretical system of Chinese medicine has been more perfect,under its guidance,also formed a more perfect gynecological diseases Treatment system,from 7 treatment of infertility,irregular menstruation and other symptoms of POF with 24 prescriptions,the group structure is reasonable,compatibility norms,get the comprehensive use of kidney,spleen,stomach,liver,blood and other methods of syndrome differentiation.For the diagnosis and treatment of POF,treatment has laid a solid foundation.However,the book does not focus on the documented disease pathogenesis analysis,for a comprehensive understanding and grasp the disease of POF.2.Qing Dynasty,there was 429 Lingnan doctors and more than 230 books during this period.Among these doctors,there were about 32 with good governance gynecological diseases,in the gynecological aspects of experience.There were 12 medical books containing gynecological or gynecological content.They had made a significant progress when compared in the past both in the theoretical system and clinical practice.According to the survival of the medical as well as in the diagnosis and treatment of POF,selected Xie Wan Qing and his book "Hui jing chan yi",He Mengyao and his book "Fuke liang fang",Liu Yuan and his book "Yi xiu zuan yao" to analysis,summed up their academic thinking and diagnosis and treatment experience.Qing Dynasty physicians on the diagnosis and treatment of POF related to the level of diagnosis and treatment has reached a certain height,creating a number of still use today,prescription,also formed a lot of later influence academic thinking,such as in patients with POF syndrome pay attention to the application of the theory of "Three Factors",pay attention to Four clinics to understand the meridians,clinical focus on the liver,kidney,spleen,stomach and other organs of the system of warming and conditioning,pay attention to the theory of liver from the proposed and operational use.Xie Wan Qing emphasis on the application of yin and yang theory in the course of gynecological diseases diagnosis and treatment,these two points in the modern major gynecological genre,especially in the treatment of ovarian disease have been in use.He Mengyao good at the connection of the olden age and today,on the basis of inheritance bold innovation,the process of treatment and attention through the four clinics to understand the meridians,this share the same view as Professor Luo Yuan Kai,Lingnan Luo’s gynecological genre important successor.He is particularly good from the liver on the amenorrhea,Water and other POF syndrome,innovative use of the soothing method of adjuvant therapy,can be considered a combination of modern psychological methods,to ease the patient,adjuvant therapy;with particular emphasis on "Three Factors" theory application,focus on the combination of Lingnan region Climate characteristics,geographical environment and the people’s physical characteristics,dialectical medication,his academic thinking of far reaching impact on future generations.Liu Yuan dare to question the experience of the sages,that treatment of amenorrhea can not be used to break the qi and blood,to promote dialectical treatment,so as to avoid accidental misuse;clinical focus on mutual care,nursed back to health,warm days,the use of viscera syndrome,eight syndrome differentiation,qi and blood syndrome and other dialectical system,flexible delivery of drugs,showing that the theory of Chinese medicine is quite solid,clinical experience.He Shouyu through the "Guang si jin dan",a book popularization of gynecological knowledge,for the transfer,the seeds have their own unique and comprehensive views,the amenorrhea syndrome is divided into two types of blood consumption and phlegm and plastic stagnation,and detailed analysis Its cause of pathogenesis,governance is the rule of law,to today’s point of view,although the understanding is not comprehensive,but to guide the clinical significance of a significant reference;he proposed that the seeds of the woman should pay attention to nourishing,Modern medicine in the treatment of infertility,to guide patients to choose to have sexual intercourse during ovulation.3.In the period of the Republic of China,Lingnan Chinese medicine education school began to develop gradually,and many folk medicine organizations were formed.Lingnan Chinese medicine gynecology has made great progress in theoretical level,medical theory and teaching materials.Selected Lu Chubai and his "Fuke zuan yao jiang yi" and Xie Zelin and his "Fuke xue jiang yi" to sum up and analysis of the two doctors in the two books written by the POF were listed as "Irregular menstruation stopped" or "Menstruation and never",for the first time in medical treatises with a special list of Chinese medicine to be generalized to a special chapter on the disease,which is in Lingnan Chinese medicine gynecologist before the unprecedented pioneering Discussion.Lu Chubai had a detailed analysis on the cause,pathogenesis,type,rule,prescription on the amenorrhea,infertility,irregular menstruation stopped.He summed up the experience of his predecessors,amenorrhea and infertility were divided into nine kinds and five kinds of syndromes,can be described as the culmination of the discussion,the basic include clinical amenorrhea and infertility common all syndromes,the selected prescription has also been used so far.Most physicians agree with the point of view,that is not caused by blood deficiency or blood dry,in fact,due to the heart liver spleen qi depression,it resulting the symptom of blood defeniency of amenorrhea,treatment should be used to smooth heart liver and spleen,and fill the heart liver and spleen qi,and then enrich the kidney;focus on inheritance classic,menstruation that the first priority is the qi and use the local flower medicine of Lingnan district,the flower is light and floating to release depression.Xie Zelin and his "Fuke xue jiang yi" is the earliest teaching material used by the Guangdong Institute of Traditional Chinese medicine.Amenorrhea and infertility were divided into two kinds and 10 kinds of syndromes,and a detailed analysis of the cause,pathogenesis,treatment and prescription medication.In the capture of"Irregular menstruation stopped",follow the point of view of Lu Chubai,the choice of Yi Jing Tang scattered liver and spleen depression,enrich kidney water,make up the heart liver and spleen qi treatment of liver and spleen and lacuna closed;in the treatment process,attention Spleen and stomach liver 3 organs and Chong and Ren veins;according to local conditions,combined with Lingnan geographical environment,climate characteristics,summarized common syndromes,commonly used tonifying yin,phlegm therapy.4.Modern Lingnan Chinese medicine gynecology,two schools in the diagnosis and treatment of POF of the literature and academic experience finishing.This part is divided into two parts,the first part of the choice of Guangdong Province,the old Chinese medicine in the Wu Zhuo Shen,Li Liyun,Shen Dingyun,Ouyang Huiqing,Luo Zhenhua and other good at treating gynecological diseases of the old Chinese medicine.Including their diagnosis and treatment of POF data,the analysis and discussion,which Luo Yuan Kai,Cai Yang Gao,Cai Chunchen and other people’ s experience in the second part of the Lingnan gynecological schools in the analysis and discussion;the second part of the selection of Lingnan two major gynecological schools:Guangzhou Luo’ s gynecological schools,eastern Guangdong Cia’s gynecological schools,The data of the diagnosis and treatment of POF were collected and analyzed.(1)The literature and academic experience of diagnosis and treatment of POF in Guangdong provinceWu Zhuo Shen thought that the amenorrhea is the actual situation is mixed with the virtual more common,will be divided into five kinds of syndromes,detailed discussion,his prescription has significant effect.In the clinical treatment of POF,he used to regulate liver and kidney,nurse Chong and Ren veins,strengthen the body resistance to eliminate pathogenic facors,tonificate and pugate in combination.Shen Dingsun thought that women with blood based,kidney based,liver for the use,summed up the treatment of infertility eight principal;clinical focus on the same disease with different governance,different disease with same treatment,and focus.on the combination of traditional Chinese and Western medicine treatment of POF.Ouyang Huijing pays more attention to Kidney controlling reproduction,emphasizing the pathogenicity of blood disorders,advocating differentiation of syndrome differentiation;that the cause of POF is organs,Tian Gui,umbilical cord blood,Chong Ren,the uterus has been sick,each other cause and effect.The essence of the kidney and spleen deficiency,liver depression blood stasis,Kidney-Tiangui-Chong Ren-Uterine axis function of premature aging;that its main pathogenesis is "deficiency" and "stasis",the former is the main reason.Among the 4 common type,the liver and kidney yin deficiency and blood stasis as the most common.In clinical,regardless of the length of the course of the disease,are to make up for the best use of the situation;focus on clear the liver,tonifying spleen and consoliate the kidney essence three methods,Regulate menstrual period,after the late,by the period and premenstrual four treatment.Luo Zhenhua summed up the experience of the development of the unicorn pills,kidney fill essence,qi and blood effects,commonly used in POF;according to their own clinical experience summed up by Tiaojing yi fang,Tiaojing er fang,Jing hou yi fang and Jing hou er fang,regulate menstrual by the time,before after the three therapy.Li Liyun advocate mildly rein force the kidney yang,nourish the kidney yin,soothing and nourishing the liver,invigorating spleen to remove phlem,clear away heat and toxic materials,promote blood circulation to dispel blood stasis,regulate qi and blood,adjust Chong Ren Du Dai veins and other flexible application;good at "the same disease with different treatment" and"Different disease with same treatment" from the comprehensive treatment,to expand the application of external law in the scope of gynecology;traditional Chinese medicine dialectical and western medicine differentiation of organic combination of treatment of infertility;heritage of the motherland medicine "medical food homologous",dialectical medicated adjuvant therapy;Clinical evidence of Chong Ren Du Dai conditioning;that the lack of kidney essence,Chong Ren deficiency is the basic pathogenesis of POF,the actual situation mixed with virtual based,when the treatment of the idea of kidney fill fine,As the treatment of POF of the basic therapy,and add her principal;the disease is divided into five types,the creation of the corresponding treatment prescription;good at the comprehensive use of traditional Chinese medicine with moxibustion,acupuncture,diet,Massage guidance and other a variety of treatment,in the treatment of POF to achieve better efficacy.(2)Lingnan traditional Chinese medicine gynecological diagnosis and treatment of ovarian premature failure of the literature and academic experience finishing and analysis Luo’s gynecological genre is one of the first batch of traditional Chinese medicine genre traditions,which has been selected for four generations.The main team has 18 members,originated from Luo Dihua,develop in Luo Yuankai,in the personnel training,the book said,medical teaching and research combined with the public and so have made some achievements in the national gynecological academic research and promotion of occupy an important academic position.In the history of Lingnan Chinese medicine gynecologist,Luo’ s gynecological school of POF related disease research the most comprehensive,systematic,book,said rich,and achieved remarkable success.This paper chooses the relevant documents of 18 inheritors to summarize.The first generation founder Luo Dihua good at febrile disease,long in a period of war,less documented literature,failed to obtain data related to premature ovarian failure.The second generation of successor Luo Yuan Kai is also an old Chinese medicine in Guangdong Province,rich in books,achievements striking.Clinical manifestations of kidney-Tiangui-Chong Ren-Uterus reproductive axis theory,in the academic community caused great repercussions,but also Luo’ s gynecological schools and the other part of the genre adhering to the main theory;in the diagnosis and treatment of POF syndrome,often with the use of Zishen yang tai wan;clinical attention to the spleen and stomach,summed up the eight spleen and stomach conditioning;is Lingnan Chinese medicine gynecologist.Related to the disease,the earlier proposed to focus on the use of blood circulation method;stressed that no prescription,pay attention to dialectical adjustment medication;four clinics to pay attention to look at the syndrome;that the amenorrhea method is the first kidney blood,and then dispersing stagnatd liver qi for relieving qi stagnation and ensure proper downward flow of the blood,there is a little heat then cooling blood,stuck with those who live with blood stasis;infertility syndrome differentiation and syndrome are divided into 5 types.The third generation successor is Zhang Yuzhen and Luo Songping.Zhang Yuzhen devote herself to the diagnosis and treatment of POF for more than 40 years,is the Luo’s gynecological schools to carry out the most relevant research,the most comprehensive of a doctor.In the understanding of the cause of POF on the innovative findings;to carry out the study of pathogenesis and drug efficacy of Chinese medicine,the formation of a series of medical treatment program;innovative proposed "Wei Zao Shuai Qi" concept for the clinical prevention of POF and early intervention Based on the traditional Chinese medicine theory to guide the clinical,syndrome differentiation,comprehensive use of traditional Chinese medicine decoction,ointment for individual treatment;focus on the treatment of qi,blood and Jing,treatment of human nature,focus on improving the quality of life of patients;treatment of POF ideas and methods can be summarized as:consoliate the kidney essence tonifying spleen,clear the liver invigorate the circulation of the blood,the combination of Chinese and Western medicine,warm the qi,make up the taste,emotional tone,maintenance treatment;early diagnosis and treatment of POF syndrome is divided into 4;in the succession of Lu’ s predecessors treatment of similar disease Based on the combination of their own clinical experience to create "Ziqui Huoxue Yi Tang(plus or minus Guishen Pills)".Luo Songping committed to the Lingnan traditional Chinese medicine gynecological genre inheritance and development work for the Lingnan gynecological college academic thinking,clinical experience of further combing and systematic research,as well as training genre successors,to promote the unique school treatment technology made a great contribution.Led the team to carry out a series of experimental research for the basic theory of Chinese medicine,"Tiangui theory","Chong Ren theory" provides a laboratory basis,but also for the POF of modern scientific research,clinical treatment to open up new ideas;that POF etiology.There are four main aspects of the pathogenesis,the actual situation is mixed,mainly kidney based,blood deficiency as the basis;clinical evidence to pay the drug based on the Lingnan area of the geographical environment and common physical characteristics,based on the dialectical treatment of Lingnan unique Chinese herbal medicine,The focus on disease and syndrome differentiation,the clinical manifestations of patients and laboratory results combined with each other to fill the kidney,blood circulation as the basic method,mainly to the traditional Chinese medicine decoction and paste form of the combination,if necessary,the appropriate use of Western medicine artificial cycle therapy comprehensive treatment.The fourth generation of inheritors,including five major successors and 9 backcourt inheritors,inherited previous academic and clinical experience on the basis of the fourth generation of inheritors and reserve inheritors also carried out a series of theories on POF and experimental research,for the diagnosis and treatment of the disease provides a useful reference.Zhu Ling focus on the diagnosis and treatment of immune POF,carried out a series of laboratory studies to further elucidate the pathogenesis of immune POF and found that Zuo Gui pills on the prevention and treatment of the disease.Shi Yun,Zhao Ying,Liao Huihui learn from Professor Zhang Yuzhen,together with the team members from different angles to carry out the clinical and experimental study of POF,to further reveal the pathogenesis of POF;found that addition and subtraction Guishen pills on the prevention and treatment of the disease.To explore its mechanism and role of action;through the mathematical model of the establishment of the possibility of POF to predict the probability of assessment of the incidence of the disease to prevent the occurrence of an effective exploration;found that patients with POF than normal anxiety,depression,anger,can not control,in the treatment should pay attention to psychological adjustment to improve the efficacy of the emergence of perimenopausal clinical manifesta... |
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