| BackgroundReflux esophagitis is caused by gastric contents against into esophageal acid reflux,heartburn and other gastrointestinal symptoms,also can cause the throat,the trachea and esophagus adjacent tissue damage of disease,is a kind of gastroesophageal reflux disease.The main complications such as esophageal stricture,Barrett esophagus.TCM no"reflux esophagitis," the name of disease,according to its primary symptom onset,attributable in ancient medical books "spit acid","acid","noisy","sick","gastric cavity pain","mei qi","despair an illusion of esophageal" category.In reflux esophagitis clinical curative effect observation,are mentioned in the literature of standardization and the importance of the standardization treatment,which can be thought of with the aid of modern science and technology to improve TCM syndrome differentiation and treatment system,formulate unified diagnostic criterion and objective rigorous treatment,is reflux esophagitis is key to the development of the modern research of traditional Chinese medicine.ObjectiveThis topic proposed from the perspective of the modern literature of traditional Chinese medicine,in domestic from 1995 to 2015,this RE literature to explore TCM treatment of 20 years,the concept of syndrome factor involved in the application of the present treatment based on syndrome differentiation type and research,so as to get RE "clinical syndrome factor-syndrome" of the corresponding relationship between the content,and on this basis,the research literature reported treatment RE sent the medication has good curative effect,of clear and the relationship between the formulas,to explore the relationship between the syndrome factor and basic drug combinations.Comprehensive arrangement,analysis and induction of RE new academic views and experience the acknowledgement,both to the RE of traditional Chinese medicine for standardization treatment,can also be generalized inductive RE disease medication regularly.MethodsBased on the Chinese medical and library of guangzhou university of Chinese medicine as a platform,included in the modern literature of traditional Chinese medicine of about of reflux esophagitis,medication rule of relevant data,collected including symptom,syndrome and drug use,establish reflux esophagitis in modern traditional Chinese medicine in clinical medicine,disease,and the database.His bluff,symptoms,the effect of drugs,sexual flavour,through statistical analysis,the use of statistical methods for frequency,correlation and cluster analysis,according to the statistical results and theoretical knowledge,summarizes the modern traditional Chinese medicine in treatment of reflux esophagitis medication experience.ResultsThis research adopts the modern literature of traditional Chinese medicine include reflux sex esophagitis diagnosis and treatment of basis 24 works and medical records of 190 cases of clinical symptoms of 128 kinds,symptoms of total frequency of 479 times.Among the more common symptoms are:heartburn,reflux,retrosternal pain,but after reflection to the chest,neck and ears back,etc.;Difficulty swallowing,laryngitis,chronic cough,asthma and other 13 symptoms,58.2%of the total;Often witness model for diseases with stomach,liver stomach wind-cold,qi deficiency and qi stagnation and blood stasis,spleen deficiency cold pixu(spleen deficient),spleen and stomach Yin deficiency,stomach heat pixu(spleen deficient)71.6%;174 flavour involving drugs,drug use frequency of total 1406 times,according to the function classification can get 20 drugs,including qi,tonifying qi,the water wet,heat medicine,wen in medicine,blood tonic medicine,phlegm cough,antiasthmatic drugs for activating blood circulation,nourish the medicine,the wet,xiaoshi drugs 11 drugs such as the cumulative frequency of up to 90.1%.High frequency of drug use is given priority to with temperature and small cold,flat,to the more to the spleen,stomach,lung,liver.Correlation analysis of high-frequency drugs prompt poria cocos and dried tangerine or orange peel,atractylodes,alisma;Dried tangerine or orange peel and pinellia tuber;Licorice root and atractylodes,ginseng,dried ginger,etc.Card type and drug related analysis,hot and humid card indicates lag and sophora japonica,Oriental arborvitae,big belly skin correlation,and blood stasis in pit and peach kernel,safflower,amber,rhizoma zedoariae,wood,platycladi seed correlation.Symptoms associated with drug analysis results showed that yellow greasy moss,mouth do litter;Pulse slip and rhizoma atractylodis;Urinating short yellow and lilac pink;Bloody and sophora japonica,Oriental arborvitae,herba schizonepetae,cortex moutan,Hot flashes sweat out and talc;Thin and chlorite schist;No correlation between urination and cattail pollen etc.ConclusionModern medicine on reflux esophagitis understanding more clearly,and in the category of traditional Chinese medicine is no unified definition,but most are visible in the acknowledgement of theory basis,the characteristics of its central idea is the same.Development to today's modern traditional Chinese medicine,combined with modern inspection,diagnosis methods and treatment,of reflux esophagitis know clearly,the definition of the disease in the spleen and stomach,and liver lung disease are closely related;Etiology and qi stagnation,qi deficiency,feeling cold and hot product,blood clotting,phlegm obstruction and blood deficiency,etc.;Pathogenesis of spleen and stomach estrangement,liver pathogenesis,qi activity block,qi and blood meridian dysfunctional lead to reverse jet,its treatment focuses on regulate spleen and stomach,liver and qi,clear and smooth qi activity;The spleen yiqi,cold temperature.The drug is given priority to with qi,tonifying qi,blood gas,heat lishi,give attention to two or morethings blood,xiaoshi to divide the source of pain.These commonly used drugs for poria cocos,dried tangerine or orange peel,liquorice,atractylodes,pinellia,angelica sinensis,rhizoma coptidis,ginseng,evodia rutaecarpa,radix aucklandiae,sichuan and fruit,rhizoma corydalis,radix paeoniae alba,etc. |
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