| Objectives: The academic experience of old Chinese medicine experts is great wealth to Traditional Chinese Medicine(TCM), to adept the TCM teaching mode-- "division with Christians" is an effective way to inherit the clinical experience and academic thought of famous TCM doctor. Professor Zhao Wenxia is the fifth installment of TCM experts in the academic experience inheritance and degree instructor,and engaged in clinical,teaching and research work for 40 years. Professor Zhao Wenxia has achieved great clinical experience at treating complex diseases, and has a unique academic ideas and clinical experience, especially for hepatitis, liver cirrhosis, non-alcoholic fatty liver disease and chronic liver disease. This study aims to explore the academic origin of Professor Zhao Wenxia’s treatment in liver cirrhosis, enhance academic thought in the treatment of liver cirrhosis. To summary a comprehensive, Systematic, objectively clinical experience and to promote the academic development of TCM in the treatment of liver cirrhosis; To develop the clinical studies of Yiqi Huoxue Lishui method of Ascites in cirrhosis, to verify the academic thought of Professor Zhao Wenxia and to provide the evidence for the clinical application.Methods: By reading the classics and the relevant literatures of TCM, toresearch mentor’s growth experience and academic origin; By studying through mentor’s tutor papers, clinical study, medical record and analysis methods, to summarize the mentor’s academic thoughts and clinical experience; By using prospective and random design, to explode curative effect of the treatment in Cirrhosis Ascites with Yiqi Huoxue Lishui Method.Results: This paper is mainly divided into three contents.Part.1 Academic origin of Professor Zhao Wenxia. Professor Zhao Wenxia has an ambition with salvation therefore she self-studied medicine as a barefoot doctor in village, and then has her undergraduate study in Henan College of TCM. In her college age, she was familiar with the Zhang Zhongjing and Li Dongyuan’theory, four great classics of TCM theory and Ming Qing Dynasties. With an open mind to learn, after graduated from the Henan College of TCM, she had studied form liver disease master--Lipu,national TCM master--Li Zhenhua and Nanjing University of TCM professor Xue Boyu. After integrated new knowledge in the long-term practice of clinical teaching and scientific research, Professor Zhao Wenxia has formed theory as Qi and blood method, spleen and stomach method, medicine and food guidance method, physical and mental method.Part.2 Professor Zhao Wenxia’s academic thoughts and clinical experience in liver cirrhosis. Academic ideas of Professor Zhao Wenxia: 1. Advocating new patterns of four clinical diagnosis and treatment of TCM: Combined with modern medical diagnosis and four diagnoses in Traditional Chinese Medicine. Biochemical test and imaging were included in the category of Listening and smelling diagnoses of TCM; Medical history was contained in the category of Physician visits; Physical examination and palpation were contained into the category of Pulse diagnosis. To inductive formulated the quantitative classification standard of sublingual collaterals change with the degree of blood stasis. The comprehensive change extent of sublingual collaterals and thecompensatory phase of hepatitis cirrhosis of the liver disease progresses was positively correlated. 2. Finding the key of disease. The key of liver disease is the disorder of qi and blood therefore the treatment should be focus on spleen and stomach: The syndrome of Cirrhosis of the liver was qi and blood. Disorder of qi and blood is the foundation of liver cirrhosis and pathogenesis. Liver and spleen plays important role in the balance of qi and blood. Professor Zhao Wenxia points that regulating spleen and stomach is the essence of the liver disease treatment. 3. Internal and external treatment. Through the therapy for the treatment of chronic liver disease by Professor Zhao Wenxia, Qihuo treatment is used for the therapy for jaundice(Yin) caused by liver cirrhosis, TCM rectum drip is used for the treatment of hepatic encephalopathy in cirrhosis hepatic. Chinese herbal medicine is used for liver cirrhosis ascites. Du Jiu treatment is used for the low immunity of cirrhosis.4.Professor Zhao Wenxia pays attention to recuperate. Professor Zhao Wenxia thinks medicinal diet nourishing the liver was lies to nursing care of the spleen and stomach; With guided theory, Professor Zhao Wenxia invents Shugan Jianpi Yangwei exercises; Professor Zhao Wenxia makes her point that Yangxin is beneficial to the liver.Professor Zhao Wenxia was good at various liver diseases, especially in installment dialectical cirrhosis of the liver. According to the symptoms of TCM and modern medicine clinical staging, cirrhosis of the liver can be divided into six types, two types in compensatory period:Ganyupixu type, Qizhixueyu type; four types in Loss compensation period:Pixushisheng type, Shireyunjie type, Pishenyangxu type, Ganshenyinxu type. A detailed record and treatment were added to each type for the comments on treatment and medication characteristics. Professor Zhao Wenxia attaches the consistency of the certificate, method, square, don’t use the unknown herbs and analysis detailed of the jaundice, ascites, hepatic encephalopathy.Part.3 Clinical Research of the Treatment in Qixuxueyu type Cirrhosis Asciteswith Yiqi Huoxue Lishui Method Objective: To observe the clinical efficacy of the Yiqi Huoxue Lishui Method on Qixuxueyu type Cirrhosis Ascites and to explore the effect of the Professor Zhao Wenxia’s academic experience on cirrhosis then to provide the evidence for Professor Zhao Wenxia’s clinical experience. Methods: A prospective, randomized, controlled clinical study model was used.106 cases of cirrhosis ascites were randomized into control group and treatment group, each group has 53 cases. In control group, simple Western medicine was adopted.Patients in treatment group oral Yiqi Huoxue Lishui decoction and use Zhushuitie for external treatment on the basis of control group.To observe abdominal water(ultrasonic testing), total serum bilirubin, alanine aminotransferase, aspartate aminotransferase, serum albumin, symptoms and signs of traditional Chinese medicine after treatment. Results:1.The difference of control group and treatment group was not significant at gender, disease duration, ascites quantity(P>0.05); The effect of symptoms curative, ascites, abdominal girth and the overall effect were shown statistical difference between control group and treatment group.The efficacy in treatment group was apparently superior than control group( P<0.05).2. The difference of control group and treatment group was not significant at ALT、AST、TBIL、ALB level before the treatment( P>0.05);After treatment, the level of ALT、AST、TBIL were reduced in both group,ALB was increase in both group. The efficacy in treatment group was apparently superior than control group( P<0.05).3. No obvious adverse reactions. Conclusion: The Yiqi Huoxue Lishui method could increase the level of ALB, reduces the level of ALT, TBIL, improves effectively the life quality and the clinical efficacy for the patients with Qixuxueyu type of cirrhosis ascites. Conclusion: This study firstly and systematic summarized the history of Professor Zhao Wenxia’s cirrhosis academic origin, clinical experience and academic thought, and to propose and verify the treatment of Qixuxueyu typecirrhosis ascites with Yiqi Huoxue Lishui method with distinct innovativeness. This study could promote the academic inheritance and development of TCM in the treatment of liver cirrhosis. |
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