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Succeeding Wang Shuchen’s The Five Zang-organs Homology Academic Thought And Bushen Tongluo Decoction On Clinical Study Of Idiopathic Pulmonary Fibrosis

Posted on:2017-05-07Degree:DoctorType:Dissertation
Country:ChinaCandidate:Q MiaoFull Text:PDF
GTID:1224330488970032Subject:Internal medicine of traditional Chinese medicine
Abstract/Summary:PDF Full Text Request
Professor Wang Shuchen is the fifth national old Chinese medicine experts in the academic inheriting experience of the instructor, respiratory disease in clinical, teaching and research work for 40 years, has a wealth of clinical experience and a high theoretical level, is a famous Chinese medicine respiratory disease experts Professor Wang Shuchen summarize the treatment of respiratory diseases Academic Thought, the theory is caused by the "Nei Jing", often emulated in Zhongjing, and the gathering Yu Zhu family, under the tutelage of Professor Xu Jianzhong, taught by many modern artists, which formed a "leave in the lungs, not only in the lung, "the five internal organs coherent treatment of respiratory diseases academic Thought. In this paper, Professor Wang Shuchen internal organs coherent thinking the treatment of respiratory diseases as the main line, summarize and inherit their academic experience.Part I:Professor Wang Shuchen internal organs coherent treatment of respiratory disease ExplorationObjective:To summarize the methods of application of Professor Wang Shuchen treatment of respiratory disease with five academic origins and characteristics.Methods:by following Professor Wangshu Chen learning, combined with the theory of traditional Chinese medicine, in-depth summary Professor Wang Shu’s academic thought and the academic origin, strive to sublimation to guide clinical academic theory; the way with the division of clinical, Q & a mentoring, diagnosis of more than teaching etc. summarize Wang of the five internal organs with the respiratory disease prevention and treatment methods.Research results: Professor Wang Shuchen five Zang-organs homology source of academic thought in treating respiratory diseases.Professor Wang Shuchen learning from Professor Xu Jianzhong, a famous combination of respiratory diseases in China, after painstakingly honed. Professor Wang Shuchen that respiratory disease of traditional Chinese medicine and when back to the Canon using of Zhang Zhongjing, play in the Tang Song. So, Professor Wang Shuchen treatment respiratory disease theory derived from within by, and Zhongjing of learn and more method, and on Xue Ji, heavy spleen kidney thought more has benefit, abandoned partisan, later medical home essence more has pick and formed has its sharp of scholarship thought and medication features.Professor Wang Shuchen for the treatment of respiratory disease five homology academic thought introduction. (1) back this seeking source, cure will seeking its fundamental; (2) different disease cure in one way, not away from lung, and more than lung, five Zang-organs homology treatment respiratory disease; (3) attention cold temperature and at regulation gas machine of lifting (4) again each to generous treatment of respiratory diseases and high efficacy.Conclusion:Professor Wangshu Chen in the long-term study and clinical practice widely sampled advantages of other medical home, respected for the treatment of respiratory disease "doesn’t leave in the lung, not only in the lung", gradually formed the academic thoughts and characteristics of five zang organs homology method for treating respiratory disease.Part II:Respiratory disease treated by Professor Wang Shuchen academic thought and experienceObjective:To summarize the clinical experience of Professor Wang Shuchen using five homological methods in treatment of respiratory disease.Methods:by following Wangshu Chen professor of learning, analysis his prescription, we calculate division means, a comprehensive summary of Wangshu Chen professor of applied five coherent thought in the treatment of cough, chronic obstructive pulmonary disease, asthma, bronchiectasis, rhinitis, blood disease after bone marrow transplantation lung drain, lung cancer drug ideas and experience.Research results:Professor Wang Shuchen in chronic cough of treatment does not completely arrested in internal injuries, and exogenous of classification method, will scholars experience summary for rule cough ten method; in clinical. Bitter effect of banxia xiexin decoction on, adjusting focus engine, combined with chronic cough treated with method of tonifying kidney and lung and distinctive, commonly used in clinical and Uncaria antispasmodic and obstinate cough, Nansha Shen nourish the lung and resolving phlegm and cough. Aster cough and constipation, non-drug, but make good use of the power.For chronic blocked sex lung disease and bronchial asthma, disease, Professor Wang Shuchen stressed specimens and rule, to adjustable fill spleen kidney method for fundamental, take II fairy, and dihuang, fill kidney gas, health pulse, and Astragalus rose fill cases gas, banxia Epsom heart adjustable Chang char to must health phlegm of source, auxiliary to earthworm, and wear mountain Dragon, and Sang Pi, and shiwei, phlegm vision lung, solutions spasm flat breath rule its standard, and on Angelica, and white mustard phlegm, and gegen flat breath, and whip grass clear lung hot, check cough and has unique of experience.For bronchial expansion syndrome, Professor Wang Shuchen think hot HIV throughout disease always, treatment to heat detoxification, and Lee lung row phlegm for first, hemoptysis most belongs to hot forced blood line, first heat cool blood bleeding for to, and carbon class drug bleeding most steady, due to support spread patients common phlegm resistance gas road generalized tonic-clonic urgent, so must and to asthma rule of law of; for stable period patients, teacher stressed "upright save within, and evil not dry", and "fire and vitality not compromise with the", health spleen fill kidney, and helped upright is key, upright foot is Tin fire elimination, no repeatedly attack of runs.For bronchial expansion syndrome, Professor Wang Shuchen think hot throughout disease always, treatment heat detoxification, and lung row phlegm for first, hemoptysis most belongs to hot forced blood line, first heat cool blood bleeding for to, and carbon class drug bleeding most steady, due to support spread patients common phlegm resistance gas road generalized tonic-clonic urgent, so must and to asthma rule of law of; for stable period patients, teacher stressed "upright save within, and evil not dry", and "fire and vitality not compromise ", health spleen fill kidney, and helped upright is key, upright foot is Yin fire elimination, no repeatedly attack of runs.Leukemia, and again barrier bone marrow transplant concurrent lung row different reaction is Professor Wang Shuchen outpatient of features disease species, King teacher think to hidden source machine of pneumonia most more see, and lung between quality disease has many similar of at, but due to deficiencies, and more with various anti-row different drug, and antibiotics, total to Qi, and kidney virtual mainly, especially Dang focuses on fill kidney, temperature kidney na gas is treatment of fundamental, junior to removing wind vision bi, and huoxue pass complex, in this disease poisoning evil not clear also not ignored, so, heat detoxification, and removing evil drug also indispensable.For variable should sex rhinitis of occurred, Professor Wang Shuchen stressed physique is main for, Lung spleen kidney virtual is easily formed allergy syndrome, so, change internal is key, fill kidney health spleen prescription this class disease in the not deficiency, but allergy season, and or rhinitis attack Shi to first rule its standard, Lung resuscitation nasal, so with Ma apricot Shi Gantang, and cocklebur child bulk, and added wild chrysanthemum, and hive, vision lung heat, and bulk pass nasal orifices, or small dragon soup temperature lung cold often can fast worked, but end must to health spleen fill kidney received work.Professor Wang Shuchen that formed by upright virtual lung cancer, caused by the toxin inside. Human organs and imbalance of yin and Yang, lung, spleen and kidney failure are the main cause of lung cancer. Traditional Chinese medicine by enhancing immune function, reduce side effects and enhance chemotherapy, radiotherapy, and can even make the long-term survival of patients with, it is important to improve the level of treatment of lung cancer. Wang Lung cancer treated by Astragalus root, ophiopogon japonicus with supplementing Qi and nourishing Yin Fu Zheng, fuzheng quxie, invigorating for deficiency, cancer, "product addition". When Yang as obvious, common curculigo orchioides, xianling, psoralen, continuous fault, Alpinia, Cistanche deserticola, dry ginger, tonifying the spleen and the kidney Yang; when deficiency is apparent, Nansha, ginseng, ophiopogon, Dendrobium, Huang Jing, moreover, Ligustrum, fill the yin essence. Miss Wang in help restore vitality are paying attention to spleen, often used in Fuling, Jiao Bai, Charred Triplet, spleen and stomach.Conclusion:Professor Wangshu Chen use five zang organs homological methods in the treatment of respiratory disease with distinct characteristics of the medication, often invigorating spleen and kidney based, supplemented by regulation of the spleen and stomach gas lift, accompanied to regulate and lung and phlegm method, for treatment of lung and not specifically the main in the lung for difficult to treat respiratory system disease treatment has good curative effect.Part III:Bushen tongluo decoction in the treatment of interstitial lung disease clinical researchBackground:In recent years, traditional Chinese medicine in IPF disease name, etiology and pathogenesis, cure therapy, and many other aspects have been exploring and formed the Qi, nourishing Yin, promoting blood circulation, removing obstruction in collaterals, even Ruanjian blood breaking methods and pharmacological research also found inhibition of TGF beta with some drugs such as flower Inula, giant knotweed rhizome, radix salviae miltiorrhizae, etc., even of collagen degradation effect. Deficiency of lung and blood stasis, Qi deficiency in the disease occurred in the development of play an important role, even the initiating factors, the traditional Chinese medicine to Qi, blood, dredging collaterals in the treatment of IPF, can enhance and improve the quality of life of patients; but most of them ignore the "kidney governing Inspiratio" this important mechanism, Wangshu Chen professor from the homology of the five zang organs of, pay attention to kidney sodium gas treatment of the disease to us with useful tips.According to the experience of Professor Wang Shu Chen five zang organs homology in the treatment of pulmonary fibrosis, Bushen Tongluo Decoction, a randomized, with N-acetylcysteine for control, for a period of 3 months of clinical research, to observe the clinical effect of Bushen Tongluo decoction.Objective:To confirm the clinical effect of the treatment of idiopathic pulmonary fibrosis with the treatment of the decoction of invigorating the kidney and dredging collaterals (Wang Shuchen).Methods1 Select 55 patients with IPF patients met the inclusion criteria were randomly divided into two groups and the control group. Observation of 28 cases,27 cases in the control group. Before the two groups in age, sex and treatment of TCM symptom scores, lung function, six-minute walking test St scale there were no significant differences. Comparability (P>0.05);2 treatment group patients party with fill kidney pass complex Tonga reduction, daily 2 times, meal half hours taking, even clothing 12 week; control group maintained Western General treatment, oral acetyl half glutathione amine acid 0.6g, daily three times, meal Qian taking, even clothing 12 week; two group patients into group Shi where application oxygen therapy and oral hormone treatment of, are by original program treatment, and records merged medication.3 clinical observation, comparing before and after treatment symptom scores, lung function and six-minute walk test and the St George’s scale questionnaire.4 statistical analysis methods:using SAS 8.2 software package for statistical analysis of measurement data (± s) that the two groups before and after treatment with paired samples t test, between the two groups were compared using independent samples t test; count information overall evaluation of both groups using non-parametric rank test.Research results:1 Treatment of breathing problems before and after comparison of the two groups: difficulty breathing after treatment than before treatment to improve the observation group (P<0.05), the control group increased dyspnea score compared with before treatment after treatment (P<0.05); the two groups before and after difference, observed group than the control group (P<0.01).2 Two group comparison of treatment before and after a dry cough:cough points compared with before treatment after treatment was observed a significant reduction (P<0.05), no difference compared with the control group before and after treatment of dry cough score (P>0.05); both groups before and after difference more obvious difference between the two groups (P<0.05), observer group than the control group.3 The treatment of symptom score between the two groups:Observer Group of symptoms after treatment than before treatment significantly reduced (P<0.05), the control group before and after treatment, no difference in symptom score (P>0.05); the two groups before and after difference were statistically significant differences (P<0.01), observer group than the control group.4 The two groups before and after a 6-minute walk distance:observed after treatment compared with walking distance 6 minutes ago (P<0.05); the control group compared with before treatment to reduce walking distance 6 minutes after treatment (P<0.05); the two groups before and after the 6 minute walking distance there was a significant difference (P<0.01) in the observation group were significantly longer than in the control group.5 Saint George symptom questionnaire score between the two groups:Group Saint George symptom questionnaire score lower than before treatment after treatment, but was not statistically significant (P>0.05); the control group increased Saint George symptom questionnaire score after treatment than before treatment, but without statistical significance (P>0.05), two sets of symptom score difference difference between before and after treatment (P<0.05), observer group than the control group. 6 before and after treatment in lung function between the two groups:VC comparison group before and after treatment showed no statistically significant (P>0.05), no statistically significant compared with the control group before and after treatment (P>0.05), before and after the treatment difference between the two groups was not statistically significant (P>0.05). Increase DLCO comparative study after treatment than before treatment, but without statistical significance (P>0.05); the control group after treatment than before treatment to reduce, but not statistically significant (P>0.05), before and after the treatment difference between the two groups was not statistically significant (P>0.05).ConclusionBushen tongluo decoction on IPF patients with breathing difficulties, dry cough, have a certain effect, can improve the clinical symptoms of patients with IPF, improve six-minutes walking distance and quality of life, but significant improvement in lung functions.
Keywords/Search Tags:Wang Shuchen, Academic thought, The five Zang-organs homology, Bushen Tongluo decoction, Clinical research
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