Optimal Treatment Of Multivessel Complex Coronary Artery Disease

Objective:Observing and analyzing major cardiac events and the medical costs among patients with multivessel complex coronary artery disease (MCCAD) during the three-year follow-up.The MCCAD patients had undergone single complete revascularization (CR), fractionated revasculariza-tion (FR) or partial revascularization (PR). and the present study aimed to screen the optimal treatment program.Methods:Clinical data of patients with multivessel coronary disease treated by PCI that had been admitted to the Department of Cardiology at the Provincial Hospital Affiliated to Shandong University between December2003and October2009were selected for the study. We collected and analyzed retrospectively, which including the general state of health, related risk factors, biochemical indicators, ECG and ultrasound of cardiology, and so on.Patients were divided into the CR,FR,and PRgroups. All the patients were followed up after the PCI, The follow-up time was36months maximum. Major cardiac events, including all-cause mortality, myocardial infarction, severe heart failure, rehospitalization and revascularization (coronary artery bypass grafting and coronary stent reimplantation), were set as the end points. In addition, the three-year medical costs associated with heart disease were analyzed. SPSS13.0software (SPSS, Inc., Chicago, IL, USA) was used for statistical analysis. Measurement data are expressed as the mean±SD and were analyzed with the t-test. The x2test was used to analyze the counting data. Logistic regression multivariate correlation analysis was also performed and P<0.05was considered to indicate a statistically significant difference. The survival curves were estimated with Kaplan-Meier.