The Correlation Of Chronic Fatigue Symdrome And Its Impact Factors And TCM Constitution And Clinical Research

Since the21st century, our country economy is in high speed development, the living conditions of people have greatly improved.But with the rapid development of economy, the pace of life is increasing rapidly, work pressure is also growing, competition is increasing fiercely. In such circumstances, the incidence rate of chronic fatigue syndrome climbed all the way. Due to its long duration and easy to break out repeatedly, the personal quality of life is greatly affectted by CFS and it has also aroused the widespread attention in medical community. The constitution of TCM is an individualized diagnosis method and it pay much attention to the study of individual constitution features, constitutional type, physical difference law and the relationship with health and disease. The constitution of TCM is extremely suitable for modern people-centric individual medical model. So in this study we do the research on chronic fatigue syndrome and its influence factors and the correlation analysis of TCM constitution, and to seek the objective basis and new ideas for individualization of TCM prevention and treatment of chronic fatigue syndrome.Purpose:On the basis of the review of the research progress of chronic fatigue syndrome and the constitution of TCM, throughing clinical randomized sampling survey, to explore the correlation between chronic fatigue syndrome and its influencing factors and constitution of TCM, and to put forward a comprehensive clinical thinking of improving the risk constitution of chronic fatigue syndrome with acupuncture, and to provide theoretical and objective basis for clinical practice syndrome-based differentiation and treatment of CFS.Methods: 1. Investigation:In142cases of patients with chronic fatigue syndrome and148cases of control group, useing the questionnaire survey combined with the international or domestic rating scale, to collecte of the main features of the two groups, work, family history and other epidemiological data, then carries on the statistical analysis. The two groups are compared by chi-square test to analyze the related factors,then conclude the factors that have statistical significance. Taking the factors again into the logistic regression analysis, to explore the correlation of the TCM constitution type and CFS and its influencing factors. Finally, put porward the acupuncture treatment ideas of TCM constitution combined with clinical on the basis of preliminary results.2. Theory research:Based on preliminary research results, combined with the literature on acupuncture, CFS risk constitution (i.e., Qi deficiency, Yang deficiency) of the ideas were discussed.3.Clinical study:choose the inclusion of60Qi deficiency and yang deficiency patients with CFS standard, using completely randomized grouping method,60cases were randomized to treatment group and control group with30cases in each. The treatment group was given acupuncture which can regulate constitution, the control group was given routine acupuncture treatment,3times a week,8times for a course of treatment, observation of treatment after3courses. The indexes of results including the overall evaluation of efficacy, symptom scores before and after treatment, the Chadler fatigue scale evaluation and evaluation of qi deficiency, Yang deficiency constitution integral.Results:1. The results of investigation:(1)Thoughing statistics analysis, there are differences of TCM constitution between the case group and control group’s physique type distribution, mainly reflected in the calm, Yang deficiency, qi deficiency constitution. Will be more than four in chronic fatigue syndrome meaningful physical type as the independent variable, chronic fatigue syndrome as a dependent variable, further logistic regression analysis. Results show that under the0.05inspection level, the independent variable qi deficiency constitution (OR=4.088), Yang deficiency constitution (OR=3.113) and the peaceful consititution (OR=0.240) and dependent variable of the relationship between the chronic fatigue syndrome was statistically significant, qi depression and chronic fatigue syndrome has no statistical significance. According to the regression coefficient and estimates OR judgments, Yang deficiency, qi deficiency of quality of traditional Chinese medicine (TCM) is positively correlated with CFS sufferer, is a risk factor for chronic fatigue syndrome occurred.(2) There was no difference in the baseline level between case group and control group such as sex, age, height, weight, etc.Main characteristics to two groups, work situation and eating habits for statistical data related to the comparative analysis, is shown in the living environment, economic satisfaction, overwork, family discord, interpersonal disharmony, career setbacks, work time is more than eight hours, dietary laws, mind you, fat GanHou greasy, tastes heavy, drink coffee, exercise habits, sleep less than7hours, personality and emotional aspects such as statistically significant.Incorporating the above factors into the mul Li-factor logistic regression, tip:in the P<0.05level, and ultimately into the regression equation of the nine factors, respectively is:X3(overfatigue), X7(overwork), X9(eating habits), X13(exercise habits), X14(less than7hours of sleep), X15(nature), X16(mood).The above7independent variables for the dummy variable quantitative, statistical results suggest:(1) X3(1) often overfatigue and occasionally (see classification) is statistically significant, and the risk factors. X3(2) sometimes overwork difference compared with occasional fatigue.(2) with little more than8hours working time compared to X7(1) X7(2) often and sometimes greater than8hours working time are risk factors of CFS, there were significant differences.(3) X9(1)diet is regular and irregular diet (reference category) were compared, there was difference between two groups, having a regular diet X9is a protective factors.(4) X13(1)Regular exercise and X13(2) sometimes movement and compared classification, statistically significant, and were protective factors.(5)X14(1)and(2) compared with the basic classification is statistically significant, and they are the protective factors.(6) X15(2) introvert relative to the mixed character introversion, there is significant difference, is the risk factor of CFS.(7) Secondary emotions and X16(1)and(2) the positive emotions, compared with the negative emotions (see classification), all have statistical significance, and both are protective factors for CFS.(3) Qi deficiency constitution has relationship with X3(overwork) X8(strong work pressure)and X9(regular diet). Often overwork is risk factors, strong work pressure and often eating regularly are protecting factor.(4) Yang deficiency constitution has no relationship with the factors.2. The results of theoretical research:Main collateral channels used for regulating qi deficiency constitution with acupuncture is the spleen, stomach, Ren and bladder. Commonly used acupuncture points are Taibai(SP3), Zusanli(ST36), Zhongwan(CV12), Qihai(CV6), spleen shu(BL20), stomach shu(BL21). Main collateral channels used for regulating yang deficiency constitution with acupuncture is the Ren and Du meridian, kidney and bladder meridian. The most common used acupuncture points are Taixi(KI3), Zusanli(ST36), Shenque(CV8), Guanyuan(CV4), Shenshu(BL23), Mingmen(GV4).3. The results of clinical research:The60patients that included study were randomly divided into treatment group and control group, with30cases in each. One of the control group patient, due to personal reasons has falled off, the final completion of clinical observation of the treatment group contain30cases, the control group was29cases.By statistical analysis, both group of patients had no significant difference in gender, age, illness, constitution structure, they can be compared. After3courses of treatment, overall curative effect comparison shows that two groups were effective, the total effective rate of treatment group was86.67%, the total efficiency of control group was72.41%. compared with two groups, the efficacy of the treatment group was significantly better than the control group, P<0.05, there was statistical significance.After treatment,the symptoms of fatigue scale, Chadler fatigue scale scores and Qi deficiency, Yang deficiency constitution score were significantly improved than before treatment (P<0.01). the integral difference comparison between groups, the treatment group in improving the fatigue symptom score, Chadler fatigue scale scores and Qi and yang deficiency constitution scale better than the control group (P<0.05), there was significant statistical differences.Conclusions: 1. Research conclusion:risk constitution of chronic fatigue syndrome is Qi deficiency and yang deficiency, protect the constitution is flat and matter; occurrence is positively related to the factors and chronic fatigue syndrome is:economic satisfaction, often diet, regular exercise. Negative correlation is:often overworked, lack of coordination, interpersonal relationship, work pressure, sleep less than7hours and negative emotion; often overworked and working pressure are risk factors of qi deficiency, often eating were protective factors of qi deficiency.2. The individual physical guidance of acupuncture treatment, acupuncture can regulate, improve individual physique; acupuncture regulating individual constitution has certain feasibility.3. For Qi deficiency, Yang deficiency in CFS patients, acupuncture modulation can significantly improve the symptoms of fatigue, and Qi deficiency, Yang deficiency constitution integral. The overall effect is better than the control group (acupuncture group); acupuncture treatment of regulating body CFS, small side effect, high security.