| This thesis consists of three parts for the study of propagation of chaos for the large Brownian particle systems with Newton and Coulomb interactions in the Rd (d≥2) space.The first part considers the N-particles interacting system with Newton potential aggregation and Brownian motions. Assuming that the initial data are independent and identically distributed (i.i.d.) with common probability density function Ï0∈= L∞(Rd)∩ L1(Rd, (1+|x|)dx), this thesis proves the following results:(a) The "propagation of chaos" for this interacting system with a cut-off parameter ε~ (lnN)-1/d and the corresponding mean-field equation is the Keller-Segel equation. (b) The Yudovich type uniqueness and stability in Wasserstein metric with initial data for the weak solution to Keller-Segel equation.(c) For d= 2, if 8Ï€v> 1, the "propagation of chaos" is valued globally in time. On the other hand, if 8Ï€v<1, the expectation of the collision time for the interacting particle system is bounded by 2Ï€Var{X10}/1-8Ï€v. For d≥3, if Ï0(x) is bounded by a univer-sal constant in Ld/2 norm, then the "propagation of chaos" is also valued globally in time. The second part is concerned with the numerical method for solving the Keller-Segel equation. A random particle blob scheme is introduced and a rigorous analysis of the convergence for this scheme is given which is mainly based on the stability of Wasserstein metric for weak solutions to the Keller-Segel equation.The third part presents a simple proof of the non-collision between particles al-most surely (a.s.) for a system of N Brownian particles with Coulomb interaction s-ince the potential is positive, and then the wellposedness of this system is obtained. In two dimension, assuming that the initial data are i.i.d. and have a common densi-ty Ï0∈= L∞(Rd)∩L1(Rd, (1+|x|2)dx),it is also rigorously proved the "Propagation of chaos" for this interacting system and showed that the mean-field equation is the Poisson-Nernst-Planck (PNP) equation. |