Cyathula Alcohol Mention Things Step-down Mechanism Of The Experimental Study

The primary hypertension is one kind of the disease affecting human being health and the quality of life gravely. The morbidity falling ill originally assumes an uptrend since the beginging of this year , the modern medicine research to the disease is already more thorough , still there are existence , large amount of scholar there existing dispute and the problem not having studied in many being that unremitting efforts but. Knowing and understanding traditional Chinese medical science to going deep into falling ill originally is to accompany integration of Chinese and western medicine but to come true step by step , there is no so far still but universally accepted systematization theory. Mount existence clinically many view, many disease coming to cure this the principle according to the diagnosis and treatment based on an overall analysis of the illness and the patient's condition, already have accumulated large amount of experience.and have got gratifying achievement.Primary hypertension machine is extremely complicated , therefore clinical medicine difficult to discriminate or use is difficult to take an effect. The faithful director Gai guo zhong professor thinks that the disease place falling ill originally is in a blood vessel in which the blood and qi circulate , pathogenesis key is that gas blood becomes estranged , blood goes against with the gas. The root of bidentate achyranthes formulating is completed under being that here theory guides, already in applying many years clinically, get fairly good clinical effect. Expound and prove for expounding the root of bidentate achyranthes decompression effect further and giving the objective's , science's in connection with mechanism. The experiment takes primary hypertension rat (SHR) as the animal model studying the marriage partner , this model are universally accepted go ahead between nations and the primary hypertension of human being approaches most. Pass the effect to SHR rat blood pressure , serum superoxide dismutase (SOD) , third dialdehyde (MDA) contents; Effect kidney organization conversion growth factor (TGF-β1) egg white is expressed; To extracorporeal culture blood vessel bast, the cell affects; The experiment that thickness affects to blood plasma PGI2 studies.The experiment bear fruit is demonstrated:1. the ethanol extracts from Cyathula officinalis Kuan is a thing being able to reduce spontaneity hypertensionrat (SHR) blood pressure;2.the ethanol extracts from Cyathula officinalis Kuan is a thing being able to reduce rat serum MDA contents at the same time notable power-ups SOD activity obviously;3. the ethanol extracts from Cyathula officinalis Kuan id a thing but reduces expressing of kidney organization cell middle TGF-β1 ;4. Being able to adjust SHR blood vessel active material coming into being and releasing , elevates blood plasma PGI2 contents;5.the ethanol extracts from Cyathula officinalis Kuan has promoting the extracorporeal culture rat chest aorta blood vessel bast cell added value effect;6.Being able to have an effect to take precautions against and restore the LPS loss to blood vessel7. In the root of bidentate achyranthes serum height, dosages may affect rat chest aorta bast cell relevance mRNA expressing obviously setthe ethanol extracts from Cyathula officinalis Kuan part effect mechanism having studied investigation and discussion originally, has provided the certain basis , our in expectation of more thorough research and investigation and discussion to the medicine knowing and studying primary hypertension theory and method.