Captopril, a representative of angiotensin converting enzyme inhibitors (ACEI), has many advantages as an antihypertensive drug, for example, it can reverse left ventricular hypertrophy and it can protect renal function in hypertensive patients with diabetic nephropathy. Although there are many reports about the clinical application of captopril, the answers to the following questions remain controversial: 1. whether captopril lowers blood pressure (BP) significantly only in high renin hypertensive patients, 2. whether captopril causes hyperkalemia and 3. whether captopril damages renal function, In addition, it was reported that captopril test has very high sensitivity and...
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