Compound Optimized Dose Ratio Of The Ed-nm-mo Triple Method

Following the development of the Globalizing Economics, internationalcompetition is becoming more and more intense, multinational corporationincreasingly endanger Chinese medicine trade in no national boundariesmarketplace. How we should rise to the challenge and catch opportunity by theforelock and compete in the Global Marketplace with multinational corporation?The most important ability we need is the Core Competence that was introducedby C K Prahalad and Gary Hamel (1990), who defined it as "an area of specializedexpertise that is the result of harmonizing complex streams of technology andwork activity." Compound is the marrow of Chinese Herb Compound. Chinese Herb Compound hasthousands years history of the formula which is the mainstream method ofdeveloping new medicine, during this period, many kinds of compound and theoryhave been accumulated. However, there are a lot of difficulties in technologyto find a solution, which will be beneficial to make the formula become the CoreCompetence to the world medicine market. Effect of Chinese Herb Compound is different from single medicine in manyways such as multiple compositions, multiple targets and the nonlinear ratioof the Compound and Effect. How to find a method which is fit for the advantagepreponderance of Chinese Herb Compound, and how to constitute a practicablesystem are serious subjects. Consequently, in 1999, Ministry of Science andTechnology of the People s Republic of China commence the national seriousbasis researching and developing plan 973 , national academician Wang YongYan is the chief scientist of the project. This project centers on the criticalkey of compound development and basis research of Chinese Medicine. The purposeof it is to fundamentally change under-developed situation of Chinese HerbCompound and to provide theory and technology basis .As a result, we can improvethe ability for predominating world medicine market and owning decision-makingpower of completely new Chinese Herb Compound. In this paper, we deem that development of completely new Chinese HerbCompound should bases on two core links and four platforms one core link isto determine effect indexes for disease and to make a prescription with chosencompounds, the other core link is to determine the best ratio of compatibilityof Chinese Herb Compound. First core link needs biology synthetically evaluatingplatform, effect of medicine matter based separating platform and pharmacologyof compound researching platform, second core link needs the best ratio ofcompatibility of Chinese Herb Compound mathematics platform. All of these英文摘要 7platforms are technology difficult points should be resolved. This paper is one part of the national serious basis researching anddeveloping plan 973 , all works center on mathematics platform for the bestratio of compatibility of Chinese medicine. The character of Chinese HerbCompound is multiple compositions, multiple targets and nonlinear, so that themathematics attribute of compound function is multiple variable, multipleattributive variable and nonlinear. The mathematics attribute of compounddecides that the best ratio of compatibility of Chinese Herb Compound mathematicsplatform must have two distinguishing qualities: one is nonlinear fittingability that conform to the nonlinear attributive of compound, the other ismulti-objective optimization ability that conform to multiple indexes. There are some questions in the optimization of Chinese Herb Compound now,firstly indexes optimizing is not at the same time, secondly nonlinear fittingability is weaken or none, finally experimental design method is simple andsingle. In this paper, we introduce a evolution scheme for the best ratio ofcompatibility of Chinese medicine problem, called Experimental DesignNonlinear Modeling Multi-objective Optimization triple-expansion metho...