| Objective Exploring the fittest anesthetic method for Roux-en-y cholecystoenterostomy in juvenile rabbits. Methods Forty New Zealand juvenile rabbits were divided into4groups by random number table:Control group (CG n=10), Nembutal group (NG n=10), ketamine group (KP n=10), Urethane group (UG n=10). During the experimental anesthetization, vital signs were monitored; anesthesia start time(AST), anesthesia time(AT), stop pain evaluation(SPE) and anesthetic accident(AA) were recorded. After operation, sensitivity evaluation (SE), mobility evaluation (ME), bowel sound time (BST) and seeking water and food time (SWFT) of the rabbits were taken notes. The effects and survive rate of these four groups on the juvenile rabbits were compared and analysed in order to discuss the most fitting anesthesia of experiment. Results AST:3.8±0.2min (NG),2.2±0.3min(UG),2.4±0.4min(KG). AT:187±7.4min (NG),279±6.9min (UG),89±5.5min(KG). SE in Post-op of NG is normal, that of KG worse and that of UG worst. ME of NG and that of KG is good and that of UG is paralysis in5cases and no independent activity. SR of our experiment is75%, highest in NG, second in KG, last in UG. Death of time in experiment was centered in1th week Post-op. Cause of death in our unit is anesthetic accident, respiratory infection, respiratory obstruction and intestinal obstruction. Complications in Post-op:NG abdominal infection in1case; KG: respiratory infection in2cases; UG:respiratory infection in2cases. Conclusions1.5%Nembutal anesthesia by ear margin of intravenous is the fittest anesthetization for Roux-en-y cholecystoenterostomy in juvenile rabbits. Objective Exploring the fittest stitching method of end-to-side jejunojejunostomy for Roux-en-y cholecystoenterostomy in juvenile rabbits. Methods Sixty Zealand juvenile were divided into4groups by random number table:SLCSG (single layer continuous suture group n=15), SLISG (single layer interrupted suture group n=15), SLCISG (single layer continuous and interrupted suture group n=15), control group (CG n=15). During operations, MESJT(medial end-to-side jejunojejunostomy time), MOT(medial operating time) and PC(perioperative complications) were recorded. After operations, SE (sensitivity evaluation), ME (mobility evaluation), BST (bowel sound time) and SWFT (seeking water and food time) of the rabbits were taken notes. Survive rate of these four groups and effects on growth and development of juvenile rabbits were compared and analysed in order to discuss the most fitting stitching method of end-to-side jejunojejunostomy for Roux-en-y cholecystoenterostomy in juvenile rabbits. Results MESJT and MOT were decreased according to the order of SLCSG, SLCISG and SLISG statistically. BST and SWFT were no difference among SLCSG, SLCISG and SLISG. They are Significant longer in experiment groups than those in CG. SE was no difference among SLCSG, SLCISG and SLISG, the worst in SLCSG. ME was the same in the experiment as in CG. SR was0%in SLCSG,80%in SLISG,93.33%in SLCISG,100%in CG. Cause of death were complications of air way and jejunojejunostomy. Laparotomy observation in Post-op1th month:intestinal adhesion was3cases in SLISG and2cases in SLCISG and no case in CG Abdominal Adhesion was10cases in SLISG. Right hepatic lobe mild sclerosis was10cases in SLISG. Abdominal adhesion and cirrhosis were no case in both SLCISG and CG The mean growth length of Roux jejunum was2.1±0.31cm monthly in SCISG,2.2±0.3cm monthly in SLCISG and2.3±0.33cm monthly in CG. The medial diameter of Roux jejunum was no difference in both SLISG and CG,0.63±0.07cm in SLCISG and0.8±0.05cm in CG but no statistical difference. Observation3rd month:intestinal adhesion was10cases in SLISG and2cases in SLCISG and no case in CG. Abdominal Adhesion was10cases in SLISG. Right hepatic lobe moderate sclerosis was10cases in SLISG. The mean growth length of Roux jejunum was2.3±0.31cm monthly in SCISG,2.3±0.33cm monthly in SLCISG and2.3±0.33cm monthly in CG. The medial diameter of Roux jejunum was no difference in both SLISG and CG,0.35±0.05cm and decrease clearly in SLCISG. Head circumstance, body length and weight was no difference in juvenile rabbit pre-operation; was decreased in experiment groups in Post-op2nd week and1th month statistically; was no reduced statistically in experiment. Upper Gastrointestinal Contrast and laparotomy in Post-op3rd month, we found no reverse flow in Roux jejunum in SLCISG and12cases in SLISG. There is mild reverse flow in1case, moderate in3cases, severely in8cases. Conclusions SLCISG is the most fitting stitching method of end-to-side jejunojejunostomy for Roux-en-y cholecystoenterostomy in juvenile rabbits. Objective Exploring the relationship between clinical result and the length of Roux jejunum for Roux-en-y bilioenterostomy in child. Methods Forty New Zealand juvenile rabbits were divided into3groups by random number table:SRJG (short Roux jejunum group, n=15), LRJG (long Roux jejunum group n=15), control group (CG n=15). During operation, MOT (medial operating time) and PC (perioperative complications) were recorded. After operation, SE (sensitivity evaluation), ME (mobility evaluation), BST (bowel sound time) and SWFT (seeking water and food time) of the rabbits were taken notes. Survive rate of three groups and effects on growth and development of juvenile rabbits were compared and analysed in order to discuss the most fitting length jejunum for Roux-en-y cholecystoenterostomy in juvenile rabbits. Results MOT was no difference between SRJG and LRJH statistically. BST and SWFT were no difference in experimental groups. They are Significant longer in experiment groups than in control group. SE and ME were the same in the experiment as in CG. SR was93.34%in SRJG and66.67%in LRJG. The cause of death were complications of air way and Roux jejunum. Laparotomy observation in Post-op1th month and3rd month:intestinal adhesion was2cases in SRJG and10cases in LRJG and no case in CG. Roux jejunum volvulus was no case in SRJG and6cases in LRJG. The growth length of Roux jejunum was2.2±0.25cm monthly in experiment groups and2.3±0.33cm monthly in CG. The medial diameter of Roux jejunum was0.63±0.07cm in experiment groups and0.8±0.05cm in CG on Post-op1th month. It was0.35±0.05cm in experiment groups in Post-op3rd month and decreased clearly. Head circumstance, body length and weight was no difference in juvenile rabbits pre-operation; was decreased in experiment groups in Post-op2nd week; was decreased in LRJG in Post-op1th and3rd month. Upper Gastrointestinal Contrast and laparotomy observation in Post-op3rd month, we found no reverse flow in Roux jejunum. Conclusions SRJ is the fittest Roux jejunum for Roux-en-y cholecystoenterostomy in juvenile rabbits. Short roux jejunum in Roux-en-y bilioenterostomy with fewer complications may be in favor of the Post-op resume and growth and development of the children. |
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