The Expression Of Gap Junction Genes Connexin 32, Connexin 43 And Their Proteins In Human Hepatocellular Carcinoma Tissues And Cell Lines And The Roles In Signal Transduction

Hepatoma is one of the most common and malignant tumors which threatens to human life. About 90% of hepatoma is hepatocellular carcinoma (HCC) . In each year, more than 250 thousand cases of HCC were reported around the world, among which 110 thousand cases (44.7%) occured in China. Due to the difficulty in early diagnosis and treatment to explore, the tumor molecular mechanisms, early diagnosis and effective clinical treatment on HCC has been a major research project all over the world.