Effects Of PCMV₄-TGFβ₁ As Nucleic Acid Vaccine On Ⅱ°Burn Wound Healing And Post-Burn Scarring In Rat

Burn is a kind of common illness, management of whose surface of wound should span the whole course of treatment. The only reliable criterion for assessing the level of treatment is the speed and quality of healing of wound. Due to inadequacy in study of the mechanism of healing of burn and scarring that follows and inadequacy in study of the contributing factors, further elevation of the level of treatment of burn is delayed to some extent. Burn not only makes patients physically and mentally suffer tremendously, also imposes a heavy economic burden on their families and society. Scholars at home and abroad have done a lot of work in recent years, but to date no satisfactory development has been achieved yet in speeding up of healing of the wound and effective control of scarring that follows.To overcome the shortcomings in preparation of scald model, a new ideal instrument, constant-temperature constant-pressure electric scalding device, is developed. Using this device, models of scald of varying degree were prepared on mice and rats. It was found that, under conditions of 80℃ in temperature and 0.5Kg in pressure, the times required for creating superficial second-degree scald, deep second-...