The Genetic Polymorphism Of Interleukin-1 Gene And Histomorphologic Changes Around Endosseous Implants

Since the development of the endosseous dental implants and their application to clinical dentistry, the oral function and cosmetic of partially or fully edentulous patients have been markedly improved. With the increasing living level of Chinese people, implant dentures have been accepted by more and more patients who want to have a comfortable, esthetic and durable denture.However, the success rate of implant treatment has not reached 100% yet. One of the main causes of implant failure is bone loss around the implants. Recent studies suggest that the risk factors for bone loss around implants are smoking, infection, mechanical loading, bone quality and metabolic diseases. In the two-stage surgical procedure, mechanical loading is absent between stage I and stage II of surgery. What's more, scholars generally regard that there is no marginal bone loss around the implants during the healing period. In fact, the marginal bone loss does really happen in this period, which may due to the potential individual factors. So it is obviously important for us to get a better understanding...