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A Study Of Variety On Excitability And Energy Elements And Relationship With The Time Of Death In The Gastrocnemius Of Rats

Posted on:2007-08-08Degree:DoctorType:Dissertation
Country:ChinaCandidate:B LiFull Text:PDF
GTID:1104360185994308Subject:Forensic medicine
Abstract/Summary:PDF Full Text Request
Estimation of postmortem interval is one of the important tasks to be firstly solved in the practical work of forensic medicine, but simultaneously it is a difficult point. To accurately estimate postmortem interval can greatly help provide important clues in criminal case detection. It has an important significance in designating the scope of reconnaissance, identifying whether suspects had criminal time, determining the nature of an offence and interpreting the crime process. At the same time, estimation of postmortem interval also has some practical significance in insurance indemnity and civil cases, such as property inheritance. Over the centuries, many scholars have carried on continuous exploration, but till now they can still not be accurately estimated. Using a variety of methods to make comprehensive analysis and estimation is still the most direct and effective way to solve problems in the basic and practical work.Using supravital reaction to estimate postmortem interval is of great significance in the estimation of early postmortem interval. Since the German scholar Galvani discovered "animal electricity" phenomenon in 1780, many scholars began to do the research on electrical excitability of skeletal muscle postmortem. Accordingly the research of estimation of postmortem interval began in 1800 (Nysten). The limitation of research means and purposes, the lack of awareness of some phenomena and correct theoretical support and guidance, results in shortcomings in the utility and reliability of the early outcome. There are few researches on using supravital reaction to estimate postmortem interval. Most are limited to the description of morphology of cadaver and mechanical excitability of muscles. However, the research on the energy and material changes in muscle organization is particularly prevalent in the sports medicine and muscle illness. There is little outcome can be directly used in the forensic medicine. Therefore, we have designed the following experiment, looking forward to providing available information in the practice of Forensic Medicine. With the research base of the predecessors, the experiment will explore effective ways to estimate postmortem interval by establishing different animal death models, using methods of combining...
Keywords/Search Tags:Skeletal muscle, Electrical excitability, Postmortem interval, Glycogen, PFK, HPLC, ATP, ADP, AMP
PDF Full Text Request
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