Preoperative Staging And Tumor Resectability Assessment Of Pancreatic Cancer: Prospective Study Comparing CDFI, EUS, HCT, And MRI

Pancreatic cancer is associated with an extremely poor prognosis, no more than 30% of patients can survive 1 year, and only 3%~7% of them can survive 5 years after the diagnosis. In China, the incidence of Pancreatic cancer keeps the trend of rising. Surgical resection remains the only chance for cure in these patients. However, surgical exploration without adequate preoperative attempts to determine resectability results in resection in only 10% to 25% of patients. Accurate preoperative Assessment of resectability of pancreatic carcinoma is essential to avoid unnecessary surgeries and, at the same, to not deny the opportunities for cure to patients with resectable diseases. In the absence of metastatic diseases, which clearly precludes resection, assessment of vascular invasion is the most important parameter for determining resectability in pancreatic cancer such as the anatomical relation between the tumor and superior mesenteric vein, superior mesenteric artery, portal vein and so on.The objective of this study was to evaluate prospectively the efficacy of different strategies based on Color Doppler Flow Imaging (CDFI), Endoscopic Ultrasonography (EUS), Helical Computed Tomography(HCT), and Magnetic Resonance Imaging(MRI) in the staging and tumor resectability assessment of Pancreatic Cancer.All consecutive patients with pancreatic carcinoma judged fit for...