Localization Of Substance P Immunoreacitivities And MRNA In The Auditory Nuclei Of Guinea Pigs, And In Relation To Hearing

Understanding what functions as transmitters is of importance in neuroscience because it is through the release of neurotransmitters that neurons communicate with one another and influence the periphery. It has been proved that acetylcholine functions as the efferent transmitters in the auditory pathways. At present, the afferent transmitter acting in the auditory system is not sufficiently identified. The recent study has suggested that some neuropeptides might function as an auditory transmitter .Substance p (SP) is a biologically acitive peptide which was first isolated from the brain and intestine. Since Chang and Leeman clarified the amino-acid composition of SP, our understanding of it has been greatly increased.Substance P, widely distributed in the central and peripheral nervous system, has been proved to play a role in the transmission of primary sensorial memory, and in a further analysis of the perception of it in the central nervous system as an important neurotransmitter or...