Effects Of Bushen Huoxue Recipe On Learning And Memory Failing And On Hippocampus Apotosis In Mice Following Transient Ischemia

Distraction osteogenesis was first applied in the craniofacial skeleton in 1992. Its use has subsequently been extended to virtually every area of the craniofacial skeleton with a great deal of success. The technique became a breakthrough in the craniofacial surgery due to its diminished morbidity, absence of relapse and less complications. This is particularly useful for the pediatric population, and holds promise for the treatment of craniofacial deformities in infants. In this paper, the history of this technique was reviewed and associated basic research and clinical applications were performed.In the experiment, the dogs of 4-6 months age underwent anterior maxillary subapical osteotomy unilaterally and the maxilla was distracted in a vertical orientation. Radiographically and histologically, all dogs fully bridged the distraction gap. Intramembranous ossification was detected. The occlusion relationship was changed simultaneously. Except for the distraction gap, the maxilla on the distracted side grew approximately at the same speed as that on the control side. The technique of distraction in the baby dogs is effective and won't impair the further growth of the maxilla. According to this, distraction osteogenesis is feasible in children without the danger to interfere the growth.The technique was applied with internal distractors in 30 cases with congenital or acquired craniofacial deformities. Selection of the proper osteotomy and distraction vector is discussed. The movement of the bone segment is analyzed. The effect of bone lengthing on the surrounding tissue was observed. With the experience of clinical work, we elucidate the appropriate latency period, the distraction rate and the fixation period. Additionally, we first applied the technique on a patient with severe craniofacial fracture and got an improvement of facial appearance.Conclusion: Distraction osteogenesis is proved successful in craniofacial skeleton. This is particular true in children with less morbidity. The technique, when used in children, won't impair the growth potential of the bone. The preoperative planning of the osteotomy and the distraction vector is the most important thing. The distraction rate and the period of latency and fixation should be adjusted in the practice. Tissue and structure surrounding...