| Background :Angina pectoris is a clinical syndrome of pernicious oxygen insufficiency of heart muscles. That is due to imbalance between oxygen demand and supply in heart muscles. The symptom usually occurs with old men of over 40 years old.Coil artery sclerosis is the most important reason of the pathology signs. That makes up some 90% in Angina pectoris. Cardiac output in artery suddenly reduced, a contradiction in term of blood demand and supply in the heart muscles are reasons that bring about Angina pectoris. On the clinical symptoms, Angina pectoris continuously alters. This is one of most important factors in artery-heart diseases found with highly recrudescent ratio as well as highly death ratio. In the recent years, patients who contract Angina pectoris make up high ratio. That becomes a threatening to human health. Hence, studies on Angina pectoris become a heated current event.Advantages of the traditional Chinese medicine in rejecting Angina pectoris are based on dialectic reasons, general harmonization, paying intensively attention vitality - blood relation, readjusting yin - yang balance, establishing a suitable new balance. That is also the purpose of Angina pectoris treatment.A method combined Chinese traditional medicine with Western one has opened up a new domain in the treatment of Angina pectoris. At present, the method becomes one of the effective approaches to dispose of Angina pectoris.Objective:By references of ancient-update documents concerned, learning precious professional experiences from the supervise professor, development process of Angina pectoris studies in contemporary medicine was summed up in the thesis. For the recent years, Anginapectoris is considered to be in precordial pain with chest discomfort (usually referring to ischemic heart disease) field. In Chinese medicine, precordial pain with chest discomfort results from leucorrhoea, unsuitable spirit, regimen, and cold . These reasons result to phlegm . Reduced circulation of vitality and blood and cold catching create blood standstill in heart artery. Kaixin capsule number II is a recipe, that the supervise professor created on his experience. It consists of the main components of Shengmai Powder, Shixiao Powder and Yueju Pill. Experiment studies have obviously proved that Kaixin capsule number II is of good effect in the treatment and prophylactic for Angina pectoris. Studies on Chinese traditional and west medicine shows that effect of Kaixin capsule number II on Angina pectoris treatment and prophylactic presented in both improvement of clinical symptoms and positive alteration in hematology index, blood fat, ECG and heart ultra-sound result.Methods:1. Document referencesThe thesis implemented bases on references of ancient medicine, abroad and domestic documents and summing up Chinese traditional-West research works of Angina pectoris. Being founded on precordial pain with chest discomfort treatment principles of ancient medicine, and on cause analysis, pathology, diagnosing and treating Angina pectoris in contemporary medicine, the thesis has advanced valuable results in Angina pectoris treatment. The results achieved in the thesis are considered to be basis for researching traditional Chinese medicament utilized in treatment and prophylactic of clinical Angina pectoris.2. Clinical symptom researchSelection of patients based on proposed criterions. In the research, 60 Angina pectoris patients are accidentally chosen. Those are divided into 2 groups: experiment and control one. Each consists of 30 patients. Clinical symptom studies are implemented in inspecting: hematology, fat group, cardiogram, heart ultra-sound and the level of clinical symptom improvement before and after treatment. In addition, Angina pectoris relapse abilities are also evaluated after using Kaixin capsule number II.Results:1. After 4 weeks of treatment of angina pectoris, Kaixin capsule number II clearly improves clinical symptom, speeds up coil circulation and protects heart muscle lack of blood (percentage of success: 86.66%);as well as effect of isosorbide dinitrate for this disease treatment (percentage of success: 90.%) (p>0.05). In addition, ECG is clearly improved (p<0.01);TC, TG, LDL-C are reduced and HDL-C is increased (p<0.05). Thus,Kaixin capsule number II readjusts concentration of blood fat. Hence, the medicine resists artery sclerosis.2. Toxic secondary effect of Kaixin capsule number II during Angina pectoris treatment process had not occurred in the research. Therefore, the medicine considered being effective and safe pharmaceutical product for Angina pectoris treatment. Using the medicine for a long time restrains intensive pain of chest, prevents acute infect of the myocardium, improves heart function, strengthens patients heath.Conclusion:1. Using Kaixin capsule number II for Angina pectoris treatment clearly helps improvement of clinical symptoms, speeds up coil circulation and protects heart muscle lack of blood. Kaixin capsule number II readjusts concentration of blood fat. Hence, the medicine resists artery sclerosis.2. Kaixin capsule number II is not of toxic secondary effects. Using the medicine for a long time restrains intensive pain of chest, prevents acute infect of the myocardium, improves heart function, strengthens patients heath, forecasts relapse of angina pectoris.
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