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Construction Of A 3-dimensional Surgical Diagnostic And Therapeutic Platform Using 3D Reconstruction Of Virtual Chinese Human

Posted on:2004-10-04Degree:DoctorType:Dissertation
Country:ChinaCandidate:D M LiuFull Text:PDF
GTID:1104360092999141Subject:Clinical Anatomy
Abstract/Summary:PDF Full Text Request
The Project "Virtual Chinese Human(VCH)" is a result of combination of advanced modem techniques covering many fields such as computer science and anatomy. Its goal is to provide digitized information of the human body for further studies in those fields, especially in medicine. In the project "Several key techniques for Digitized Virtual Human", one of the national "863" great projects, the key part, or the dataset collecting work was assigned to our institute. I was honorably enrolled for it. Then part of the dataset collected was utilized to generate 3-dimensional model, or technically 3D-reconstruction, as the primer part of my doctorial study. Based on these models, some application tries in medicine were mde.After the dataset of VCH Female l(VCH-Fl) were completely collected,, further upgrades were made in techniques in dataset collecting. We employed these upgraded techniques in the second period of dataset collecting, that of a male. The dataset collected, called VCH-M1 (Virtual Chinese Human Male 1), were characterized in the slice interval of the same 0.2mm, including 9232 anatomical serially sectioned slices(up to 161.56 GB), and radiological data composed of 1720 CT images with scan thickness of 1mm and 780 MRI images with that of 2mm. We succeeded in eliminating the deformation of the chest and the abdomin during embedding, using a technique of fixation under salty environment with low temperature, and also a technique of sequentially embedding with enough ice pieces. For good results of the chemical fixation, the carbolicacid-nitrous acid solution was modified. Serially-sectioned slices were timely labeled during specimen milling and dataset collecting. These technical upgrades help achieved excellent image quality, which would be favorite to high-quality 3D reconstruction.1426 serially-sectioned slices of VCH-M1 including the thoracic part and the neck were taken as a source of 3D models in my doctorial study. The softwares Photoshop and Amira were respectively adopted for 2D and 3D image processing. A technical route of reconstruction was followed: from single organs to regional anatomical structures ,to finally the whole thoracic part. A thoracic 3D model pool was established, composed of main structures including thyroid cartilage, criocoid cartilage, arytenoids cartilage, trachea, esophagus, main branches of great arteries and veins, sternal stem, clavicle, lungs and bronchi, and heart. The components could also classified into 2 categories, i.e. contour labels with two different solving powers , and surface models of main organs and the chest itself. The models could be showed in several ways. When poured into CT information, the thoracic models could be added to spacial relation to the whole-body model. During reconstruction, a processing skill of data with large volume, and also the reconstruction strategy were introduced. The model pool possessed great application values for its enriched features in model showing and measuring.With the model pool and the 3D animation software Maya4.5, a 3D platform for surgical diagnosis and therapy was built. Using abundant tools of Maya, we could simulate varieties of operations in sugeries, such as incision, stitching, ligation, different types of anastomoses, deformation of organs and also the case of tumors. Still a skeletonized whole-body model was created for showing free styles of poses, such as surgical pose. Through this part of study, a framework of the platform was established based on the achievement of VCH. In this platform many operations and abnormal anatomical features could be lively simulated. The platform also served asan application pattern in clinical medicine.In the last part, a VCH pre-experhnent was introduced, which was performed with a heart. The heart was perfused with a glutin solution of 30% concentration. After that it was embedded with two steps to guarantee its anatomical position. A special machine tool were used to mill the heart, and the slices were scanned. A series of image processing was...
Keywords/Search Tags:Reconstruction
PDF Full Text Request
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