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The Study Of Tetrandrine Affecting To BIU-87 And BIU-87/Adm Cells

Posted on:2004-05-13Degree:DoctorType:Dissertation
Country:ChinaCandidate:Y S LiFull Text:PDF
GTID:1104360092487036Subject:Surgery
Abstract/Summary:PDF Full Text Request
Cell Culture And Morphology In BIU-87 And BIU-87/ADM Being Affected By TetrandrineAbstract ObjectivecTo observe the growth of BIU-87 and BIU-87/ADM cells, andmorphology after affecting by tetrandrine. Methods: Phase contrast microscope, MTT assay and transmissionelectron microscope were used in the experiment. Results: Growth suppression and apoptosis were found in the BIU-87 and BIU-87/ADM cells after intervention by tetrandrine. Their growth suppression curve were coincidence, and apoptotic body being seen in the cells with transmission electron microscope.Conclutions: Tetrandrine can suppress the growth of BIU-87 and BIU-87/ADM cells , induce the apoptosis. The cells did not have drug resistance against tetrandrine.
Keywords/Search Tags:tetrandrine, cell culture, apoptosis, tumor of bladder
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