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Keyword [synthetic lethality]
Result: 1 - 20 | Page: 1 of 2
1. Targeting DNA Repair Pathway In The Treatment Of Breast Cancer:Preclinical And Clinical Study
2. A Novel Drug Combination Suppresses KRAS-mutant Cancers
3. Design, Synthesis And Biological Evaluation Of PARP-1 Inhibitors
4. Synthetic-Lethality Screening For Critical Genes Involved In Drug Resistance Of Pancreatic Cancer
5. Delivery Of Small Interfering RNA With Micelleplex From Polymer Micelles For Cancer Therapy
6. Studies On The Anticancer Activity And Mechanism Of Simmiparib,a Novel Inhibitor Of Poly(ADP-ribose) Polymerase
7. Screening And Evaluation Of Anti-tumor Activity Of PARP Inhibitors
8. Synthetic Lethality Effects Of Ikk? Inhibition And Base Excision Repair Blockage On AML Cells
9. BRD4 Inhibition Is Synthetic Lethal With DHFR Inhibition In Pancreatic Cancer And The Mechanism
10. Mechanistic Study Of Synthetic Lethal Vulnerability In Malignant Tumors Harboring ERBB3 Or P53 Gene Mutations
11. Targetirng The ?H2AX-MDC1 Axis For Cancer Therapeutics
12. Synthetic Lethality And Mechanism Of Action Between ATR Inhibitor VE821 And Alantolactone In SW480 Colorectal Cancer Cells
13. Preliminary Study On Synthetic Lethal Effect Of P53-VEGFR2 In Glioma Cells
14. Synthetic Lethal Targeting Of Oncogenic MYCN In Neuroblastoma Via Bortezomib-mediated Proteasome Inhibition
15. Development Of Leading Compounds Of Inhibitors Targeting EZH2 Based On Synthetic Lethality
16. Synthetic Lethality Of Combined AT-101 With IDA In Acute Myeloid Leukemia Via Blockage Of DNA Repair And Activation Of Intrinsic Apoptotic Pathway
17. Targeting the loss of VHL: Induction of chemical synthetic lethality
18. Epigenetic Regulation And Function Of TMEM176A In Lung Cancer
19. The Study Of The Mechanism And Synergistic Lethal Effect On SHP2 Inhibitor SHP099 Together With AKT Inhibitor MK-2206 In Colorectal Cancer
20. Functional And Mechanistic Studies Of A Novel Oxabicycloheptene Sulfonate Selective Estrogen Receptor Modulator
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