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Keyword [Antifolates]
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1. The Design And Synthesis Of A Novel Series Of Pyrrolo[2,3-d]Pyrimidines As Antifolates
2. Development And Mechanistic Studies Of Novel Therapeutics Towards Pancreatic Ductal Adenocarcinoma By Combining PI3K,mTOR And ERK Inhibitors,or Targeting One-carbon Metabolism
3. Design, Synthesis And Biological Evaluation Of Pyrrolo [2,3-d] Pyrimidines
4. Design And Synthesis Of 4-substituted Quinazoline-7-formamide And 6-substituted Pyrrole [2,3-d] Pyrimidines
5. Design,Synthesis,Biological Evaluation And Molecular Modeling Of Novel Classical And Non-Classical Folic Acid Antagonists
6. Mechanism and function of mammalian folylpoly-gamma-glutamate synthetase
7. Design and synthesis of antifolates as inhibitors of dihydrofolate reductases in opportunistic pathogens (Pneumocystis carinii, Toxoplasma gondii)
8. The therapeutic targeting of folate recptor alpha positive tumors via folate receptor-selective novel 5-and 6- substituted pyrrolo [2,3- d] pyrimidine antifolates
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