Clinical Study On Oral Administration, External Application And Combined Internal And External Application Of Jiawei Wuwei Xiaodu Yin In The Treatment Of Thai Damp-heat Syndrome Acn

Purpose:This study is based on the collection of clinical cases,with the purpose of basic and clinical research on the treatment of aesthetic diseases with integrated traditional Chinese and western medicine.By comparing the efficacy and prognosis of the treatment of acne with damp heat syndrome in Thailand by taking Jiawei Wuweixiaoduyin orally,applying Jiawei Wuweixiaoduyin externally and using Jiawei Wuweixiaoduyin internally and externally,this study provides the corresponding theoretical basis for the evaluation of the efficacy and safety of the treatment of aesthetic diseases with integrated traditional Chinese and western medicine.Material and method:Collect the Thai patient population for online video diagnosis and treatment from November 2021 to August 2022,screen a total of 120 cases that meet the diagnostic criteria of western medicine and traditional Chinese medicine and the inclusion criteria,and divide the study cases into three groups on average,namely,observation group,observation group B and control group.Observation group A(40 cases)was treated with Jiawei Wuweixiaoduyin decoction for 30 minutes,observation group B(40 cases)was treated with Jiawei Wuweixiaoduyin decoction for 30 minutes,and control group(40 cases)was treated with Jiawei Wuweixiaoduyin decoction for 30 minutes,while control group(40 cases)was treated with 200 ml Jiawei Wuweixiaoduyin every morning and evening.The three groups were treated for four weeks with seven days as two course of treatment for four consecutive courses,and the curative effects of the three groups were recorded by observation.Finally,use Microsoft Office Excel 2019 software to summarize and analyze the case information,and use SPSS 26.0software for statistical analysis after sorting out the basic data.Results:1.There was no significant difference in age,gender,and disease course between the three groups before treatment(P>0.05),which were comparable.2.There was no significant difference in the skin lesion index before treatment,1 week and 2weeks after treatment(P>0.05).After 3 weeks and 4 weeks of treatment,there——were significant differences in the skin lesion index among the three groups(P<0.05).The skin lesion score of observation group A was significantly lower than that of the control group,while the skin lesion index of observation group B was significantly higher than that of the control group(P<0.05).The effective rates of the three groups were 82.5%,45.0%,and 62.5%,respectively,with significant differences(P<0.05);the ineffective rates were 5%,5%,and 2.5%,respectively,with no significant differences(P>0.05).3.Course of disease,acne grade,and acne score before treatment were all independent influencing factors of treatment effect or recovery(P<0.05),and age had no significant effect on treatment effect or recovery(P>0.05).4.The three groups all had a low rate of adverse reactions and no serious adverse reactions.The incidences of adverse reactions were 2.5%,5.0%,and 2.5%,respectively,and the difference was not statistically significant(P>0.05).5.The three groups all had a low recurrence rate,and the incidences of adverse reactions were5.0%,7.5%,and 7.5%,respectively,and the difference was not statistically significant(P>0.05).Conclusion:1.The use of Jiawei Wuweixiaoduyin through internal consumption,external application,and combination therapy has demonstrated a significant level of efficacy in treating damp-heat type acne.The combined therapy method has been found to be the most effective,whereas the simple external application method has the lowest efficacy.Further optimization of the administration method is required.2.Jiawei Wuweixiaoduyin has shown greater efficacy in treating patients with a low disease course,low acne grading,and low pre-treatment acne scores.The therapy has exhibited consistent efficacy across different age groups.3.The internal consumption,external application,and combination therapy of Jiawei Wuweixiaoduyin have demonstrated a low incidence of adverse reactions and a considerable level of treatment stability,making it a more patient-friendly option in clinical practice.