| Purpose:To collect clinical data of female acne patients of childbearing age through questionnaire,and make statistics on TCM syndrome types,Western medicine classification,Western medicine grading,menstruation and TCM constitution types,etc.,to explore the correlation between TCM syndrome types and Western medicine classification,menstruation and TCM constitution types,so as to provide more detailed diagnosis and treatment basis for clinic.Material and method: A unified "Female Acne Questionnaire" was designed according to the research purpose by adopting the method of epidemiology,which included the "TCM Constitution Classification and Evaluation Self-Test Table" issued by the China Association of Traditional Chinese Medicine.A questionnaire survey was conducted among300 female acne patients of reproductive age,and the situation was judged according to the survey results.SPSS26 software was used for statistical analysis of the collected data.The correlation between TCM syndrome type and Western medicine classification,menstruation and physical condition was analyzed.Results:1.General information: Among the 300 female acne patients,they could be divided into five groups according to age group: 14-21 years old,22-28 years old,29-35 years old,36-42 years old and 43-49 years old.Most of the patients were unmarried and childless.Most of the female acne patients had college or undergraduate education,and their BMI was in normal state.In the distribution of family history,fathers account for a higher proportion of family history.2.Relationship between TCM syndrome differentiation and acne in female patients: Most patients with Chong Ren disorder were aged 29-49 years old.The difference of TCM syndrome differentiation and age distribution was statistically significant(p<0.05).The disease course of patients with wind-heat in the lung is less than one year,that of patients with damp-heat accumulation is 1-3 years,that of patients with blood stasis and phlegm is 3-5years,5-7 years,and that of patients with flushing-ren disorder is 1-3 years.The difference between the disease course of acne and the distribution of TCM syndrome differentiation types is statistically significant(p<0.05).Most of the rashes in patients with wind-heat were papular;most of the rashes in patients with damp-heat accumulation were pustular;most of the rashes in patients with blood stasis and phlegm were nodular and cyst;the rashes in patients with flushing-ren disorder were papular and pustular,and the distribution difference between TCM syndrome type and rash type was statistically significant(P<0.05).In the degree of lesions,the degree of lesions in patients with wind heat was mild(grade I).Most of the patients with damp-heat accumulation and impulse disorder had moderate lesions(gradeⅡ).Most of the patients with blood stasis and spittoon were classified as severe lesions(gradeⅣ),and there was a correlation between TCM syndrome differentiation and the distribution of lesions(P<0.05).The skin lesions of the patients with wind and heat in the lung were more likely to occur in the forehead and cheek.The skin lesions of the patients with dampness and heat accumulation are better in the cheek and around the mouth.Patients with blood stasis and spittoon usually have skin lesions on the cheek.In patients with Chong Ren-disorder,skin lesions were more likely to occur in the perioral,mandibular and buccal parts,and there was significant difference in TCM syndrome differentiation and distribution of the main sites of skin lesions(p<0.05).3.Related to menstruation: the number of patients with aggravated premenstrual acne ranked the first,and the type of menstrual cycle of patients with acne type of cyst was mainly in the later period.In the patients with acne types of aggregation,nodule,pustular and papular type,the menstrual cycle types were mostly regular,and the nodular type accounted for the highest proportion.There was a correlation between the distribution of acne types and menstrual cycle types in women(p<0.05).Most of the patients with Chongren disorder had late menstrual cycle type,and irregular menstrual cycle type accounted for the largest proportion of syndrome types.There was a correlation between TCM syndrome differentiation and menstrual cycle type distribution of female acne(P<0.05).In abnormal menstruation,blood clots accounted for 93.55% of the rushing and Ren disorders,89.39% of the blood stasis and spittoon,intermenstrual bleeding accounted for 40.86% of the rushing and Ren disorders.Among the accompanying symptoms of menstruation,breast distension and pain were easy to occur,while blood stasis and spittoon were easy to occur irritability and irritability,both of which had statistical difference in distribution(P<0.05).4.Constitution related: 42 cases showed a single TCM constitution,and the number of cases ranked from most to least as damp-heat,Yin deficiency,Yang deficiency,peace quality,phlegm-dampness quality,qi deficiency,qi stagnation quality,blood stasis quality and characteristic quality.In all the constitution patients,the number of cases from more to less is in order of damp-heat quality,Qi stagnation quality,phlegm-dampness quality,Yin deficiency quality,Yang deficiency quality,peace quality,blood stasis quality,qi deficiency quality,characteristic quality.The most common constitutions of the patients with wind-heat in the lung were damp heat,peace and quality.The most common constitutions of patients with damp-heat accumulation were damp-heat and phlegm-dampness.The most common constitutions of patients with blood stasis and spittoon were damp-heat,qi stagnation and phlegm-dampness.The most common constitutions of patients with Chong Ren disorder were damp-heat quality,Qi stagnation quality and Yin deficiency quality.For damp-heat,patients with damp-heat syndrome type accounted for the largest proportion in the syndrome type,accounting for 31.03%.There was statistical significance in the distribution difference of different constitution types in different TCM syndrome types(P<0.05).Both peace and Yin deficiency(β=2.903)and Yin deficiency(β=1.179)had significant positive effects on lung wind-heat syndrome.Yang deficiency quality(β=2.239),phlegm-dampness quality(β=1.294)and damp-heat quality(β=1.194)had a significant positive effect on damp-heat accumulation.Phlegm-dampness quality,Qi-stagnation quality and characteristic quality had significant positive effects on blood stasis and coagulation.Blood stasis and Qi stagnation had significant positive effects on preventing any disorder(P < 0.05).Conclusion:1.The peak age of female acne patients is 22-28 years old,and most of them are unmarried,uneducated,and oily.2.The TCM syndrome differentiation of female acne patients is mainly based on the imbalance of thoroughness and conception.Therefore,the clinical treatment should pay more attention to the method of toning kidney Yin and regulating liver qi.The TCM syndrome differentiation of female acne patients is correlated with age,course of disease,type of skin lesion,degree of skin lesion and main site of occurrence.The skin lesions of blood stasis and phlegm coagulation syndrome are relatively severe.3.The menstrual cycle,blood clots,intermenstrual bleeding,breast pain,irritability and irritability of female acne patients are related to TCM syndrome differentiation and classification.Therefore,in clinical practice,attention should be paid to menstrual acne,so as to give preventive and holistic treatment.4.There is a correlation between TCM syndrome differentiation and TCM constitution type in female acne patients.Gentleness and Yin deficiency are related to the wind-heat syndrome of lung meridian.Yang deficiency,phlegm dampness and dampness heat are the key factors of dampness and heat accumulation syndrome.Phlegm dampness,qi stagnation,and special characteristics of blood stasis and phlegm coagulation syndrome;Both blood-stasis and Qi-stagnation constitutions have significant positive effects on the balance between conception and conception disorders. |
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