| Background:To investigate the effect of sleep apnea hypopnea syndrome(SAHS)on the outcome of radiofrequency ablation of atrial fibrillation(AF).It has been proved that SAHS is part of the mechanism involved in the occurrence of AF.However,there are few studies on the effect of SAHS on the prognosis of patients with atrial fibrillation after radiofrequency ablation.This paper aims to explore the relationship between SAHS and the effect of various variables.Methods:Patients with atrial fibrillation who underwent radiofrequency ablation after polysomnography monitoring in Chinese Academy of Medical Sciences-Fuwai Hospital,from January 2019 to December 2020 were selected,and patients with severe congenital heart disease,severe liver and kidney insufficiency,and malignant tumors were excluded.In the acute episode of cerebrovascular disease,acute coronary syndrome,infection,or a history of surgical operations within 3 months;Or patients with incomplete hospitalization data and follow-up data were followed up for recurrence of postoperative atrial fibrillation.The relationship between baseline disease status,cardiac ultrasound,SAHS and AF recurrence was analyzed.Results:A total of 845 patients with atrial fibrillation who underwent radiofrequency ablation after polysomnography monitoring in Fuwai Hospital,Chinese Academy of Medical Sciences from January 2019 to December 2020 were collected.Patients with severe congenital heart disease,severe liver and kidney insufficiency,and malignant tumors were excluded.In the acute episode of cerebrovascular disease,acute coronary syndrome,infection,or a history of surgical operations within 3 months;Or patients with incomplete hospitalization data and follow-up data,a total of 498 patients were included in this study,which were divided into two groups,SAHS group and non-SAHS group.There were 252 cases in SAHS group,including 194 males,aged 60.1±9.4 years,169 cases complicated with hypertension(67.1%),101 cases with hyperlipidemia(40.1%),39 cases with diabetes(15.5%),17 cases with valvular disease(6.7%)and 11 cases with hyperthyroidism(4.4%).Cardiomyopathy in 11 cases(4.4%);Stroke in 4 cases(1.6%);113 patients(44.8%)took anticoagulants for more than 1 year.There were 246 cases without SAHS,including 163 males aged 57.1 ± 11.3 years,120 cases complicated with hypertension(48.8%),79 cases with hyperlipidemia(32.1%),34 cases with diabetes(13.8%),20 cases with valvular disease(8.1%)and 16 cases with hyperthyroidism(6.5%).Cardiomyopathy in 4 cases(1.6%),stroke in 8 cases(3.3%);116 patients(47.1%)took anticoagulants for more than 1 year.If divided into recurrent af group and non-recurrent AF group,recurrent AF group:Age:59.1±10.59(years old),average heart rate:78.3±20.4(beats/min),anteroposterior left atrial diameter:39.5±5.9(mm),BMI:25.8 ± 3.3,SAHS in 76 cases(30.1%),non-Shah in 92 cases(37.4%);Non-recurrent atrial fibrillation group:age 57.6±10.5(years),average heart rate 78.1±21.3(times/min),anteroposterior left atrial diameter 39.4±6.1(mm),BMI 25.7±3.0,SAHS in 776 cases(69.9%),non-SHAH in 154 cases(62.6%)There were no significant differences in gender composition,proportion of patients with diabetes,hyperlipidemia,valvular disease,hyperthyroidism,cardiomyopathy,stroke and taking anticoagulant drugs for more than 1 year between the two groups(P>0.05).Age,mean heart rate and anteroposterior left atrial diameter of patients with SAHS were significantly higher than those without SAHS(P<0.001).The proportion of hypertension in patients combined with SAHS was higher than that in patients without SAHS,the difference was statistically significant(P<0.001).The proportion of patients with persistent af in SAHS group was higher than that of patients with paroxysmal af,and the difference was statistically significant(P<0.001).Conclusions:Preoperative SAHS does not affect the recurrence rate of atrial fibrillation after radiofrequency ablation... |
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