The Effect Of Radiofrequency Catheter Ablation On Left Atrial Diameter And Recent Prognosis Of Patients With Paroxysmal Atrial Fibrillation

Objective: The repeated episodes of paroxysmal atrial fibrillation(PAF)can cause the left atrial enlargement,reduction of cardiac function,mural thrombus formation,serious complications such as heart failure,embolism,and threatening the patients life and health.The purpose of the study was to observe the efficacy and safety of radiofrequency catheter ablation(RFCA)on patients with PAF,by comparing the effect of RFCA and drug therapy on left atrial diameter and recent prognosis.Method:56 patients who had RFCA indication with PAF were assigned into two groups according to the willingness of patients and their families for surgery: RFCA group(32cases)and control group(24cases).In one-year follow up,the recurrence of atrial fibrillation(AF),rehospitalization,thromboembolic events and related complications were recorded.Left atrial diameter(LAD),right atrial diameter(RAD),left ventricle diameter(LAD),right ventricle diameter(RAD),left ventricular ejection fraction(LVEF),left ventricular posterior wall(LVPW)were observed by ultrasonic cardiogram before and after one year treatment.SPSS21.0 software package was used to process all date.Measurement date was represented with mean ± standard deviation,and count date was represented with the rate or the percentage.Independent sample T-test or paired T-test was used the inter-group comparison.P<0.05 was defined as statistical significance.Result: 1 Clinical date of two groups of patients56 patients divided into two groups: RFCA group and control group.There was no statistical significance difference between two groups in terms of Age,gender,weight,height,history of atrial fibrillation,past proportion of hypertension,past proportion of diabetes,LAD,RAD,LVD,RVD,LVPW,LVEF when admitted to hospital.2 Comparison of ultrasonic cardiogram indexes in two groups before and after 0ne year treatment 2.1 Comparison of ultrasonic cardiogram indexes in the RFCA group before and after one year treatmentThe date of LAD in RFCA group was decreased(35.13±3.66 mm vs 37.03±4.43 mm,P=0.000).Therefore,radiofrequency catheter ablation can reduce the left atrium diameter after one year treatment.There were no statistical significance differences on RAD,LVD,RVD,LVPW and LVEF in the RFCA group before and after one year treatment.2.2 Comparison of ultrasonic cardiogram indexes in the control group before and after one year treatmentAmong the control group,the date of LAD was increased(39.79±3.97 mm vs 37.92±3.92 mm,P=0.000),the date of LVD was increased(49.38±5.20 mm vs 47.33±5.26 mm,P=0.023).Showing one years later,left atrium diameter and left ventricle diameter were increased after drug therapy.There were no statistical significance differences compared with admission in RAD,RVD,LVPW and LVEF.3 Comparison of ultrasonic cardiogram indexes between two groups after one year treatmentCompared with the control group,the date of LAD was lower(35.13±3.66 mm vs 39.79±3.97 mm,P=0.000),the date of LVEF was higher(65.58±5.71% vs 61.78 ± 6.88%,P=0.280)in the RFCA group after one year treatment.While,it’s mean compared with the medicine conservative treatment,radiofrequency catheter ablation can reduce the left atrium diameter,and improve left ventricular ejection fraction.There were no statistical significance differences between two groups in terms of RAD,LVD,RVD and LVPW after one year treatment.4 Comparison of Recent Prognosis among two groups after one year treatment 4.1 After one year,30 cases in the RFCA group restored sinus rhythm.1 case considered as asymptomatic recurrence of atrial fibrillation.The other one,due to intolerance symptoms of atrial fibrillation re-hospital again.4.2 One year later,15 cases in the control group restored sinus rhythm.4 cases readmission on account of recurrence of atrial fibrillation.Among 4 cases,1 case was suffered acute left heart failure,2 cases were accompanied by new cerebral infarction.2 cases progressed to persistent atrial fibrillation.3 cases still for PAF.Conclusions:Compared with the drug therapy,radiofrequency catheter ablation in patients with PAF can reduce the recurrence of atrial fibrillation,shrink the left atrium diameter,and improve the patients’ quality of life.