| Purpose:(1)By investigating the constitution of patients with primary dysmenorrhea,analyze their susceptible constitution and related factors.(2)In this study,Jingtongning Prescription was used to treat patients with primary dysmenorrhea of Yang deficiency and blood stasis type,and the clinical efficacy and safety of Jingtongning Prescription for primary dysmenorrhea were evaluated by analyzing the improvement of scores before and after treatment.Materials and Methods: The selected cases in this clinical observation were all from gynecological outpatients in the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from September 2019 to November 2021.Firstly,200 patients with primary dysmenorrhea were investigated according to TCM Constitution Classification and Judgment Table,and their susceptible constitutions and some related factors were analyzed.Secondly,60 patients with yang deficiency and blood stasis were treated with Jing Tong Ning Modified Recipe,which was taken one week before menstruation until the end of menstruation,and the course of treatment was three menstrual cycles.By observing the improvement of clinical symptoms,VAS score and TCM syndrome score before and after treatment,the clinical efficacy of Jing Tong Ning prescription,in treating primary dysmenorrhea of Yang deficiency and blood stasis type was comprehensively evaluated.Results:1.The predisposition of patients with primary dysmenorrhea is in the top three places: blood stasis(32.5%)> yang deficiency(21%)> qi stagnation(16.5%).Among 65 cases of blood stasis,10 cases of qi stagnation(23.8%)and 9 cases of yang deficiency(21.4%)are the most compatible and inclined constitutions.Among 42 cases of yang deficiency,11 cases of blood stasis(26.8%)and 10 cases of qi deficiency(24.4%)are the most compatible and inclined constitutions.Among the 33 cases of qi stagnation,9 cases of phlegm dampness(26.5%)and8 cases of blood stasis(23.5%)are the most compatible and inclined constitutions.2.In the investigation of constitution type and age distribution,disease course distribution and pain degree distribution,there was no significant difference between different constitution types(P > 0.05).3.According to the investigation of stress in life and work,the average stress accounted for46.0%;38.5% of them are under high pressure;15.5% had no pressure.4.According to the investigation of sports,21.5% of them exercise regularly;22.0% of them exercise regularly;56.5% of them do not exercise too much.5.According to the survey of body mass index,22.5% of them are underweight;Normal weight accounted for 33.5%;Overweight accounted for 28.0%;Obesity accounts for 16.0%.6.According to the survey of diet,58 people(30.0%)have no partiality in diet,68 people(34.0%)like raw and cold food,44 people(22.0%)like spicy food,30 people(15.0%)like fatty sweet food.7.Clinical efficacy analysis of dysmenorrhea before and after treatment with Jing Tong Ning prescription: before treatment,1 case was mild(1.7%),26 cases were moderate(43.3%),33 cases were severe(55.0%),after treatment,44 cases were mild(73.3%),16 cases were moderate(26.7%),and 0 cases were severe(0%).The score of clinical symptoms of dysmenorrhea before and after treatment was 13.87±2.48 and 5.93±2.41,respectively.The difference before and after treatment was P<0.05,which was statistically significant.8.The curative effect analysis of VAS score before and after treatment with Jing Tong Ning prescription: VAS score before treatment was 7.28±1.33,and after treatment was 1.78±1.32,the comparison before and after treatment was P<0.05,which was statistically significant.9.Analysis of curative effect of TCM syndrome before and after treatment with Tongning Prescription: TCM syndrome score before treatment was 16.85±2.41,and after treatment was 3.83±3.16,and the score comparison before and after treatment was P<0.05,which was statistically significant.Among them,6 cases were cured(10.0%),39 cases were markedly effective(65.0%),12 cases were effective(20.0%),3 cases were ineffective(5.0%),and the total effective rate was 95%.10.The scores of TCM syndromes(pain in lower abdomen,duration,unsmooth menstruation,dark menstrual blood,blood clots in menstrual blood,aversion to cold limbs)before and after treatment with Jing Tong Ning prescription were significantly lower than P<0.05.11.No adverse reactions were found during the treatment with Jing Tong Ning prescription,and all indexes were in the normal range.Conclusion:1.Through the investigation and study of the constitution types of primary dysmenorrhea,it is found that blood stasis,Yang deficiency and qi stagnation are closely related to primary dysmenorrhea,and there are more compatibility and tendency among the three types of constitution.2.Through the investigation and study on the constitution types of primary dysmenorrhea,it was found that the constitution types of patients with dysmenorrhea had no obvious correlation with age distribution,disease course distribution and pain degree distribution.3.Through the investigation and study of the constitution types of primary dysmenorrhea,it was found that the patients’ life and work pressure,eating habits,exercise,weight factors and primary dysmenorrhea have a correlation.4.In the clinical study of primary dysmenorrhea,it was found that the clinical symptom scores,VAS scores,TCM syndrome scores and multiple TCM single syndrome scores of patients were effectively improved after treatment with Jingtongning Prescription,showing outstanding curative effect.5.Jing Tong Ning Prescription is safe and reliable in the treatment of primary dysmenorrhea,which is worthy of wide application. |
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