Clinical Observation Of Qian Li Yang Mo Decoction Combined With Estrogen And Progesterone Artificial Cycle In The Treatment Of Intrauterine Adhesions Of Kidney Deficiency And Blood Stasis

Method:This topic is to observe the treatment of Qian Li Yang Mo Decoction combined with estrogen and progesterone artificial cycle on patients with kidney deficiency and blood stasis type intrauterine adhesions(IUA)after transcervical resection of adhesion(TCRA)posterior uterine adhesion score,menstrual status score,endometrial thickness in late proliferation,uterine artery ultrasound,traditional Chinese medicine(TCM)syndrome score,changes in the expression of estrogen receptor(ER)in the endometrial tissue on the surface of the adhesion zone,and objective evaluation of the turtle Whether Diyangxue Decoction combined with estrogen and progesterone artificial cycle treatment has clinical advantages for uterine adhesions of kidney deficiency and blood stasis type,summarize the theoretical basis and advantages of Qian Li Yang Mo Decoction in traditional Chinese medicine.Result:Using a stratified random grouping method,the patients’ hysteroscopic uterine adhesion scores before treatment were divided into three compatibility groups:mild,moderate,and severe,and the subjects were assigned to the treatment group and the control group.36 cases in each group,using superiority clinical research.The two groups weretreated with hysteroscopic uterine adhesion decomposition,the control group was treated with estrogen and progesterone artificial cycle for 2 months after the operation,and the Chinese medicine-loaded group was treated with Qian Li Yang Mo Decoction combined with estrogen and progestin artificial cycle for 2 months after the operation.Observe the uterine adhesion score,menstrual status score,endometrial thickness in the late stage of proliferation,uterine artery ultrasound,TCM syndrome score,ER expression on the surface of the adhesion zone,and pregnancy before and after the treatment of TCRA.The clinical effect of Yangxue Decoction combined with estrogen and progesterone artificial cycle and whether it has clinical advantages.Conclusion: 1.The age,course of disease,number of uterine surgery operations,number of abortions,pre-treatment uterine adhesion score,menstrual volume,menstrual color,quality score,TCM syndrome score,and endometrial thickness during proliferation in the Chinese medicine loading group and the control group,The ratio of peak systolic velocity/end diastolic velocity(S/D)level of uterine artery blood flow during systole/end diastolic velocity(S/D)level,uterine artery pulsation index(pulse index,PI)level,P>0.05,There is no statistical difference,and they are all comparable.2.(1)Comparison of intrauterine adhesion scores: both the TCM loading group and the control group could improve the degree of intrauterine adhesion of patients(P<0.05),and significantly reduced the score of intrauterine adhesion of patients(P<0.01),and the TCM loading group was better than the control group.(2)Comparison of menstrual status score: both TCM loading group and control group could improve the menstrual status score of patients(P<0.05),and TCM loading group was better than control group;Both the TCM loading group and the control group could improve the menstrual status,menstrual color and quality score(P<0.05),but there was no significant statistical difference between the two groups(P>0.05).Before treatment,there was a significant statistical difference(P<0.05)in the score of menstrual status and menstrual days between the two groups,that is,they were not comparable.(3)Comparison of endometrial thickness: both the TCM loading group and the control group could improve the endometrial thickness of patients in the late proliferative stage,with statistically significant difference before and after treatment(P<0.05),and compared with the control group,the improvement effect of the TCM loading group was more obvious.(4)Comparison of uterine artery condition: there was no statistical difference between TCM loading group and control group in the change of uterine artery S/D level before and after treatment(P>0.05).Both TCM loading group and control group could reduce uterine artery PI value(P<0.05),which reflected the increase of diastolic flow,and TCM loading group was better than control group.(5)Comparison of ER expression in the intimal tissue on the surface of the adhesion zone: The positive rate of ER expression in the intimal tissue on the surface of the adhesion zone changed before and after treatment,but there was no statistical difference(P>0.05).(6)There was no statistical difference in the improvement of pregnancy rate between TCM loading group and control group(P>0.05).(7)Total effectiveness:1)Comparison of syndrome efficacy: the total effective rate of syndrome efficacy in the control group was 77.8%,and the total effective rate of syndrome efficacy in the TCM loading group was 100%,showing a statistical difference between the two groups(P<0.05),indicating that compared with the control group,the TCM loading group was more excellent in improving the efficacy of TCM syndromes.2)Comparison of clinical efficacy: After 2 menstrual cycles,the total effective rate of the control group was 80.6%,and the total effective rate of the TCM loading group was 94.4%,showing a statistical difference between the two groups(P<0.05),indicating that compared with the control group,the TCM loading group was more excellent in improving the comprehensive efficacy.